Vědecký poradní výbor evropských akademií (European Academies Science Advisory Council - EASAC) sdružuje akademie věd členských zemí EU, Norska a Švýcarska. Záměrem EASAC je připravovat evropským politikům nezávislá vědecká stanoviska a doporučení - každoročně vydává několik souhrnných zpráv nejen pro politiky, ale i laickou veřejnost., Oceans and seas play a crucial role in regulating our climate, nurturing biodiversity, and providing income and food to people around the world. At COP21, governments across the globe agreed that a more aggressive limit for global warming should be set as an essential step toward a more stable relationship between the ocean and climate. In spite of this positive direction, however, marine sustainability faces many challenges, according to a new report issued by the European Academies of Science Advisory Council (EASAC) and the European Commission's Joint Research Centre., and Ondřej Prášil.
The paper focuses on building a vertical organisational structure
of notable parties in the Habsburg Monarchy in the 1860s and 1870s on the example of the National Party (Old Czech Party). It analyses contemporary press, announcements of political offices, correspondence of political leaders and the protocol of the parliamentary club. The key issue is the motivation of the leadership of emerging notable political parties (deputies, political leaders) to expand the party organisation from the top down (to town, district, and regional level) and its urgency in the context of forming a new political system and emerging national political
conflicts in Bohemia. The paper outlines a gradual building of connections between the political centre (the Prague leadership of the National Party) and local, or regional, centres; searching for so called local trustees and the problem with their mobilisation during
elections. The author deals also with organisational and structural changes of the political relations between the centre and the peripheries in the first twenty years after reintroduction of constitutionalism and parliamentarism in the Habsburg Empire
(from recruiting local trustees, through assembling local election committees, to founding local and regional political societies).
Th is development is put into the context of forming district government and of Bohemian election battles, which in the 1870s took place virtually every year. and Článek zahrnuje poznámkový aparát pd čarou
Active radio technologies associated with the A2/AD concept of the East as well as passive Stealth and opto-electronic systems of the competing West have become a direct successor of missile and nuclear technology related to the elimination of the intermediate-range and shorter-range missiles treaty (INF Treaty) from 1987. Guided missiles and nuclear charges (employing ionizing radiation) developed in the laboratories of the Nazi Germany and the democratic United States during the World War II were setting the world events through the whole generation - since the Cuban Missile Crisis (1962) to the collapse of the Soviet Union (1991). The INF Treaty reduced nuclear weapons significance at the global level and thus increased a role of local/regional interests and allowed for a development of information technologies leading to globalization. Now, after thirty years of internet and mobile networks development the situation has been changing slowly again. The INF Treaty has been abandoned and missiles are coming back on the scene, the nuclear alpha radiation, however, is being replaced by the electromagnetic radiation with a higher military usage potential. Though we do not know what we can expect in the next thirty years, still it is good to describe the starting point.
Vzestup české fyziky na přelomu 19. a 20. století je neodmyslitelně spjat s činností jedné velké osobnosti, zakladatele Fysikálního ústavu české university v Praze Čeňka Strouhala .Od jeho narození uplynulo 10. dubna 2010 právě 160 let., Jan Valenta., and Obsahuje bibliografii
Ruminants are often fed a high-concentrate (HC) diet to meet lactating demands, yet long-term concentrate feeding induces subacute ruminal acidosis (SARA) and leads to a decrease in milk fat. Buffering agent could enhance the acid base buffer capacity and has been used to prevent ruminant rumen SARA and improve the content of milk fat. Therefore, we tested whether a buffering agent increases lipid anabolism in the livers of goats and influences of milk fat synthesis. Twelve Saanen-lactating goats were randomly assigned to two groups: one group received a HC diet (Concentrate: Forage=60:40, Control) and the other group received the same diet with a buffering agent added (10 g sodium butyrate, C4H7NaO2; 10 g sodium bicarbonate, NaHCO3; BG) over a 20-week experimental period. Overall, milk fat increase (4.25±0.08 vs. 3.24±0.10; P<0.05), and lipopolysaccharide levels in the jugular (1.82±0.14 vs. 3.76±0.33) and rumen fluid (23,340±134 vs. 42,550±136) decreased in the buffering agent group (P<0.05). Liver consumption and release of nonesterified fatty acid (NEFA) into the bloodstream increased (P<0.05). Phosphatidylinositol 3-kinase (PI3K), protein kinase B (AKT) and ribosomal protein S6 kinase (p70S6K) up-regulated significantly in the livers of the buffering agent group (P<0.05). It also up-regulated expression of the transcription factor sterol regulatory element binding protein-1c (SREBP-1c) and its downstream targets involved in fatty acid synthetic, including fatty acid synthetase (FAS), stearoyl-CoA desaturase (SCD-1) and acetyl-CoA carboxylase 1 (ACC1) (P<0.05). The BG diet increased insulin levels in blood (19.43±0.18 vs. 13.81±0.10, P<0.05), and insulin receptor was likewise elevated in the liver (P<0.05). Cumulatively, the BG diet increased plasma concentrations of NEFA by INS-PI3K/AKTSREBP- 1c signaling pathway promoting their synthesis in the liver., L. Li, M. L. He, K. Wang, Y. S. Zhang., and Obsahuje bibliografii