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1. Assessment of placental and maternal stress responses in patients with pregnancy related complications via monitoring of heat shock protein mRNA levels

Creator:
Hromadníková, Ilona, Dvořáková, Lenka, Kotlabová, Kateřina, Kestlerová, A., Hympánová, Lucie, Novotná, Veronika, Doucha, Jindřich, and Krofta, Ladislav
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, abstrakt z konference, and TEXT
Subject:
komplikace těhotenství--krev, stres fyziologický, proteiny tepelného šoku--analýza--krev, messenger RNA--analýza--krev, ženské pohlaví, lidé, and těhotenství
Language:
Czech and English
Description:
Ilona Hromadnikova, Lenka Dvorakova, Katerina Kotlabova, Andrea Kestlerova, Lucie Hympanova, Veronika Novotna, Jindrich Doucha, Ladislav Krofta and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

2. Clinical significance of lymphocyte-platelet adhesion, cytokines and endothelial dysfunction in the development of gestational hypertension

Creator:
Matyakubova, Salomat Aleksandrovna
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, hodnotící studie, and TEXT
Subject:
hypertenze indukovaná těhotenstvím--etiologie--patofyziologie--patologie, trombocyty - adhezivita, cytokiny--krev, endoteliální buňky, endotel--patologie, TNF-alfa--krev, lymfocyty--patologie, interleukiny--krev, rizikové faktory, oxid dusný--krev, mladiství, dospělí, ženské pohlaví, lidé, těhotenství, kohortové studie, and statistika jako téma
Language:
English
Description:
The aim of our study was to determine the significance of lymphocyte-platelet adhesion (LPA), interleukins, transforming included 139 pregnant women aged between 17 and 27 years (21.3±4.22 years). GH was diagnosed in 119 women after 20 weeks of pregnancy. 20 patients (control group) were with physiological course of pregnancy. The distribution of patients by groups was carried out according to the level of blood pressure (BP) in accordance with ICD-10 (Geneva, WHO, 2002). The survey was conducted at the moment of detection pregnancy from 7 to 10 weeks and in dynamics of I, II and III trimesters of gestation. In the dynamics of gestation, were studied the number of desquamated endothelial cells circulating in the systemic circulation (CECs), nitrates levels, the adhesion of platelets by estimation their ability to form co-aggregates with lymphocytes by determining the percentage of lymphocytes aggregates with thrombocytes (lymphocyte-platelet plugs), at risk of hypertensive disorders, especially after 20-22 weeks of gestation and later, lymphocytes ability to platelets adhesion is rose, the concentrations of pro-inflammatory cytokines and NO level are increased. The direct relationship indicates their importance in the pathogenesis of hypertensive disorders in pregnant women., Salomat Aleksandrovna Matyakubova, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

3. Dědičné nádorové syndromy s možnou manifestací prenatálně

Creator:
Plevová, Pavlína and Grečmalová, Dagmar
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, abstrakt z konference, and TEXT
Subject:
nádorové syndromy dědičné--genetika--prevence a kontrola, prenatální diagnóza, ženské pohlaví, lidé, and těhotenství
Language:
Czech
Description:
Pavlína Plevová, Dagmar Grečmalová
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

4. Diagnostika mozaiky chromozomu 16 - kazuistika

Creator:
Kilijánová, Dita, Hynek, Martin, Rašková, Dagmar, Hejtmánková, M., Smetanová, Dagmar, Bečvářová, Věra, Trková, Marie, Horáček, Jiří, Stejskal, David, and Tomek, Viktor
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, kazuistiky, abstrakt z konference, and TEXT
Subject:
mozaicismus, chromozómy lidské, pár 16--genetika, trizomie--diagnóza, prenatální diagnóza, cytogenetické vyšetření, potrat eugenický, dospělí, ženské pohlaví, lidé, and těhotenství
Language:
Czech
Description:
D. Kilijánová, M. Hynek, D. Rašková, M. Hejtmánková, D. Smetanová, V. Bečvářová, M. Trková, J. Horáček, D. Stejskal, V. Tomek
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

5. Experiences and views of pregnant women on smoking

Creator:
Kaasik­Aaslav, Urve, Vanatoa, Mare, and Kotka, Ene
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, and TEXT
Subject:
kouření--epidemiologie--psychologie--škodlivé účinky, postoj ke zdraví, sociálně ekonomické faktory, průzkumy a dotazníky, epidemiologické studie, poruchy vyvolané užíváním tabáku--epidemiologie--patofyziologie--psychologie, motivace, odvykání kouření--psychologie--statistika a číselné údaje, ženské pohlaví, lidé, and těhotenství
Language:
English
Description:
Backround: Worldwide, approximately 1 billion people, from which 200­250 million are women, smoke. Based on the Estonian Medical Birth Register data, in 2010, 7,5% of pregnant women were smokers, and in 2012, 7% of pregnant women were smoking during their pregnancy. Thus, smoking rates among pregnant women fell only 0,5%. The objective of the research was to find out the views of pregnant women who were smoking during pregnancy of the effect of smoking on the health of them and their babies, and experiences in quitting smoking, changing indicators, e.g. smoking and socioeconomical status (initial exposure to smoking, employment, long­term partnerships etc.) in 2009­2013. Methods: This research is a phenomenological study, which was being carried out from October 2009 until January 2013. Data collection methods were semi­structured interviews with 45 pregnant women smoking during their pregnancy and being registered for antenatal care in three health care institutions of Republic of Estonia. An inductive approach for qualitative analysis was used. Results: Most women smoking during pregnancy started smoking in their teens, their parents smoked, they were under 30 years old housewives or unemployed. On an average of 11­20 cigarettes were consumed each day, the pregnancy of the research group did not influence frequency and tobacco intake. The participants in the research group reported that tobacco consumption helped them relax, gave them a chance to spend time in a good company, and it was not regarded as a bad habit but a social addiction, being caused by availability of tobacco products. Although most of them had an opinion about harmful effects of smoking, e.g. a cough, asthma and rapid fatigue, on the health of them and less on their expected babies, they continued smoking. Conclusions: The smoking and socioeconomical status of women smoking during pregnancy in 2009­2013 has not changed, health awareness of them is low and has not improved. Support groups with close relatives are needed to motivate cessation. In the first place, prevention needs a good example, purposeful cooperation, which starts in daily life context at homes, in educational institutions and in the community. Limiting the availability of tobacco products, postponing and preventing an initial exposure to smoking are thought to be of great importance. The results of the research will be introduced in health care institutions and they can be used in the health promotion process., Urve Kaasik­Aaslav, Mare Vanatoa, Ene Kotka, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

6. Fetálna orálna meningokéla

Creator:
Gábor, Martin, Ferianec, Vladimír, Papcun, P., Križko, Marián, Redecha, Mikuláš, and Čierna, Zuzana
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, kazuistiky, and TEXT
Subject:
meningokéla--embryologie--ultrasonografie, ultrasonografie prenatální, prenatální diagnóza, potrat eugenický, ženské pohlaví, lidé, and těhotenství
Language:
Czech and Slovak
Description:
M. Gábor, V. Ferianec, P. Papcun, M. Križko jr., M. Redecha jr., Z. Čierna
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

7. Inverze dělohy po porodu - kazuistika

Creator:
Pešková, Iva
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, kazuistiky, and TEXT
Subject:
inverze dělohy--etiologie--chirurgie, komplikace porodu--etiologie--chirurgie, vedení porodu, porodnické chirurgické výkony, dospělí, ženské pohlaví, lidé, and těhotenství
Language:
Czech and English
Description:
Inversion of uterus is very rare and serious complication of childbirth. It is a situation with very high maternal morbidity and mortality, whitch can lead to developement of very serious periparthal bleeding, DIC, neurogenic and haematologic shock. In 50% without any risk factor. This case report demonstrates this acute case which was caused by then physiologic partus until then and it shoud demonstrate some eventuality to solve this emergent situation including the method used in this case - partially successful reposition attempt of uterus using vaginal path and resulting laparotomia., Inverze dělohy je velmi závažnou a naštěstí poměrně vzácnou komplikací III. doby porodní. Jedná se o stav s vysokou mateřskou morbiditou i mortalitou, při němž může velmi snadno dojít ke vzniku život ohrožujícího krvácení, diseminované intravaskulární koagulopatie a rozvoji hemoragického a neurogenního šoku. V 50 % případů vzniká bez jakéhokoli rizikového faktoru. Tato kazuistika demonstruje tento akutní stav vzniklý při, do té doby, fyziologicky probíhajícím porodu a nastiňuje několik možností k řešení této urgentní situace včetně toho námi zvoleného – částečně úspěšný pokus o repozici dělohy vaginální cestou a následnou laparotomii., Iva Pešková, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

8. Metotrexát v léčbě ektopické gravidity

Creator:
Zdeňková, Anna, Fanta, Michael, and Calda, Pavel
Format:
electronic, electronic resource, and remote
Type:
model:article, article, Text, and TEXT
Subject:
lidé, ženské pohlaví, těhotenství, mimoděložní těhotenství--diagnóza--farmakoterapie, methotrexát--aplikace a dávkování--farmakologie--kontraindikace, abortiva nesteroidní--aplikace a dávkování--škodlivé účinky--terapeutické užití, choriogonadotropin lidský - beta subjednotka--krev, výběr pacientů, intravenózní infúze, výpočet dávky léku, rozvrh dávkování léků, and způsoby aplikace léků
Language:
Czech and English
Description:
Ektopická gravidita je závažným a potencionálně život ohrožujícím stavem. Časná diagnostika rozšiřuje terapeutické možnosti. Medikamentózní terapie pomocí metotrexátu (MTX) se stala jednou z bezpečných a efektivních alternativ. Metotrexát je antagonista kyseliny listové, jeho funkce spočívá v inhibici jejího metabolismu. Díky tomu dochází k inhibici růstu rychle proliferujících buněk, jako jsou embryonální, fetální či buňky trofoblastu. Jsou popisovány dva hlavní režimy podávání MTX. U vhodně vybrané skupiny pacientek je úspěšnost metody až 90%., Ectopic pregnancy is a common and serious problem, with a significant morbidity rate and the potential for maternal death. The earlier diagnosis of unruptured ectopic pregnancy allows the use of more conservative treatment options. Medical treatment with methotrexate (MTX) has become a safe and effective means of treating ectopic pregnancy. Methotrexate, a folic acid antagonist, acts by inhibiting the metabolism of folic acid. Methotrexate stops the growth of rapidly dividing cells, such as embryonic, fetal, and early placenta cells. There are two commonly used MTX treatment protocols – single and multidose regimens. With proper patient selection, success rate approach 90%., Anna Zdeňková, Michal Fanta, Pavel Calda, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

9. Micronized progesterone as a neuroprotector in pregnant women with post-trauma brain syndrome

Creator:
Tsyganenko, Irina Vasilivna, Simrok, Vasil Vasilyovich, and Ruban, Katerina Sergiivna
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, hodnotící studie, and TEXT
Subject:
postkomoční syndrom--farmakoterapie, progrese nemoci, gliový fibrilární kyselý protein--krev, progesteron--terapeutické užití, komplikace těhotenství--farmakoterapie--krev--prevence a kontrola, hematoencefalická bariéra--účinky léků, neuroprotektivní látky--terapeutické užití, komplikace porodu--prevence a kontrola, duševní poruchy--prevence a kontrola, dospělí, ženské pohlaví, lidé, and těhotenství
Language:
English
Description:
The present article is concerned with the study of glial fibrillary acidic protein (GFAP) level in the blood serum of pregnant women with posttrauma brain injury syndrome (post­TBI syndrome) as the marker of hematoencephalic barrier status and predictor of obstetric and perinatal complications development., Irina Vasilivna Tsyganenko, Vasil Vasilyovich Simrok, Katerina Sergiivna Ruban, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

10. Může být sonografické vyšetření nebezpečné?

Creator:
Doležal, Ladislav
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, abstrakt z konference, and TEXT
Subject:
ultrasonografie prenatální--normy--škodlivé účinky, hodnocení rizik--statistika a číselné údaje, ženské pohlaví, lidé, and těhotenství
Language:
Czech
Description:
Ladislav Doležal and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public