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62. The combined operation the cancer of the rectum with germination in genital organs
- Creator:
- Bobokulov, H. B. and Hakimov, A. M.
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- nádory rekta--komplikace--terapie, nádory ženských pohlavních orgánů--terapie, chirurgie operační--metody, výsledek terapie, dospělí, staří, ženské pohlaví, lidé, lidé středního věku, and mladý dospělý
- Language:
- English
- Description:
- The Purpose of the study: define the indications and contraindications to, combined operation in locally invasive tumor of the rectum. The Material and methods of the study: we have analysed results combined operation in cancer of the rectum with germination in genital organs, performed in department of coloproctology in National Oncological Scientific centre during 20052009 years. Under observation were 118 women at age from 21 to 68 years. This before 45 years 26 patients, from 46 to 59 years 54 patients, 60 and above years. The Results and their discussion: Postoperative complications suppurativeinflammatory character appeared beside 36 patients (30,5%), most of all after abdomeno perineal extirpation of rectum (35,5%) and abdominoanal resection of the rectum (33,3%). In lesser extend after front resection of the rectum and after operation Hartman (28,5% and 22,7%). The General lethality has formed 3,4%, have died after combined operation 4 patients from 118 operated patients. The Conclusion: thereby, brought data evident that such important factors, as frequency of the origin relapse (28%), 5year probability of survival (37,1%), under combined interference and operation of the standard volume in the cancer of the rectum practically the same., H. B. Bobokulov, A. M. Hakimov, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
63. The disease girshprunga beside adult: modern approaches to diagnostics & treatment
- Creator:
- Mirzahmedov, M. M., Ahmedov, M. A., and Sapaev, D. A.
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- Hirschsprungova nemoc--diagnóza--terapie, popis nemoci, příznaky a symptomy, pooperační komplikace, výsledek terapie, mladiství, dospělí, ženské pohlaví, lidé, mužské pohlaví, lidé středního věku, and mladý dospělý
- Language:
- English
- Description:
- The Material of the study has formed 78 sick, found on stationary treatment in Republican Scientific Centre Coloproktologii since 1992 on 2010. As it is seen, from table, from 78 sick mans was 58(74,3%), womans 20(25,7%). 19(24,3), sick were at age from 15 before 20 years, 49(60,2%) at age from 21 before 40 years and 13 (16,6%) sick from 41 before 60 years. The Main complaint sick at arrival were a stubborn constipations, which noted beside 70 (89,7%) sick, including absence of the independent chair existed beside 55(70,5%), but beside 54(69,2%) sick were noted periodic stomachache, growing on measure of the absence of the chair. The Ballooned belly existed beside all 78 (100%) sick moreover beside 20(25,6%) of them flatulence was constant. The Sickness and retching existed beside 24(30,7%), weakness, reduction to capacity to work beside 52(66,6%), increasing of the temperature of the body beside 10(12,8%), paradoxical diarrhoeas beside 6(7,6%) sick. Endoskopicheskiy method (rectoromonoscopy, colonoscopy) turned out to be else less informations 51,8% coincidences of the diagnosis. So we biopsy on Svensonu executed beside all sick, entered with suspicion on disease Girshprunga. In our observations from 78 sick beside 42(53,8,1%) were aboveanalni, beside 20(25,6%) sick rectalis, beside 13(16,6%)rectosigmoideys , beside 2(2,5%) leftside and beside 1(1,2%) sick subtotalis form hipoganglios. At biopsies on Svensonu on observations, from 78 sick, beside 44(56,4%) is revealled hipoganglios, but beside 35(44,8%) аganglios rectum. As can be seen from presented tables, from 78 sick beside 68(87,2%) us is executed onemoments radical operation, 10(12,8%) sick is as far as possible made resection hipoor aganglionarnaya of the zone, decompensate part of the large intestine and is formed colostomy. In all events at operations. The Remote results executed radical operation on cause disease Girshprunga traced from 1 before 10 years beside 57(73%) sick. The Results of the surgical treatment were valued on scale Vezika: good, satisfactory and unsatisfactory. In our observations beside 46(80,7%) sick results came in well, beside 10(17,5%) satisfactory and beside 1(1,8%) sick was an unsatisfactory result., Mirzahmedov M. M., Ahmedov M. A., Sapaev D. A., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
64. The instant results of preoperative hepatic artery chemoembolization in hepatocellular carcinoma developed on the background of cirrhosis
- Creator:
- Juraev, M. D., Nematov O. N., and Yusupbekov, A. A.
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- předoperační péče, hepatocelulární karcinom--terapie, jaterní cirhóza--terapie, chemoembolizace terapeutická, výsledek terapie, staging nádorů, and lidé
- Language:
- English
- Description:
- Importance: Treatment of hepatocellular carcinoma remains a topical issue of Clinical Oncology. More than 80% of cases hepatocellular carcinoma develops in the presence of liver cirrhosis. These patients are doomed, many clinics they held only symptomatic treatment and life expectancy of patients is not more than 6 months. The main reason for the refusal of surgeons and Chemotherapeutists of treatment is associated cirrhosis. Purpose: To improve results of surgical treatment of liver cancer developed on cirrhosis Materials and methods: We analyzed the immediate results of treatment of 12 patients with hepatocellular carcinoma developed on a background of liver cirrhosis. From the large size of the tumor and associated liver cirrhosis, these patients the first stage of oil produced by hepatic artery chemoembolization of the affected lobe of the liver tumor. After 2 3 weeks performed liver resection. Results: After analyzing the results, we concluded: chemoembolization reduces tumor volume and weight, increases the physiological regeneration of hepatocytes unaffected tumor fraction, improves functional performance of the liver and does not affect the frequency and severity of postoperative complications., Juraev M.D., Nematov O.N., Yusupbekov A.A., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
65. The main approaches to the development of innovative pharmaceutical industry of the Russian Federation in the context of globalization
- Creator:
- Klunko, Natalia and Marynia, Reta
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- farmaceutický průmysl--ekonomika--statistika a číselné údaje--trendy and lidé
- Language:
- English
- Description:
- Pharmaceutical industry - one of the few areas in which innovations affect all of us, because ultimately have a direct impact on the duration and quality of life for us and our loved ones. In the presence of a strong market and a lack of understanding of the need for innovation is necessary, in our opinion, investing in basic research and facilitate the process of innovation in the pharmaceutical industry by the state and society. For the targeted development of pharmaceutical industry seems appropriate to determine at the state level prospects for the domestic pharmaceutical industry and its role in the international market, and develop a drug "doctrine" of Russia. This paper analyzed the problems of the state associated with the pharmaceutical market in the globalization period. Also investigated the theoretical aspects of the modern study of globalization in the light of the analysis for the global pharmaceutical industry and analyzes the major political and economic factors that have the most significant impact on the production of pharmaceuticals., Natalia Klunko, Reta Marynia, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
66. The role of lymphodissection in rectal cancer surgery
- Creator:
- Navruzov, S. N., Abdujapparov, S. B., Akbarov, E. T., Navruzov, B. S., and Islamov, H. D. B.
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- nádory rekta--chirurgie, lymfadenektomie--využití, pooperační komplikace, přežití, staging nádorů, výsledek terapie, anastomóza chirurgická, metastázy nádorů, statistika jako téma, ženské pohlaví, lidé, mužské pohlaví, and lidé středního věku
- Language:
- English
- Description:
- Aim of investigation: to study immediate and remote results of standard and extended lymphodissection in patients with rectal cancer. Material and methods: 132 patients with rectal cancer were performed radical surgery with lymphodissection in D2 and D3 volume according to a height of tumor location. In immediate postoperated period there were noted complications in 4 patients that made up 3,03%. Observation time was 5 years. Tumor recurrence was reported in 5 patients (3,8%). In remote period metastases were revealed in 8 patients (6,6%). 5year total survival rate was 78,5±4,2% at stage II. 5year total survival rate was 56,4±3,7% at stage III. Comparing the results of standard and extended lymphodissection it was noted statistically authentic increase of 5 year survival rate in patients at stage III. Obtained data allow to come to the conclusion about reasonability of performance of different variants of lymphodissection for patients with rectal cancer at stages II and III., Navruzov S. N., Abdujapparov S. B., Akbarov E. T., Navruzov B. S., Islamov H. D., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
67. The study drug pathomorphism and immunohistochemical parameters of tumor in endoarterial of regional long-term chemotherapy in treatment of cervical cancer
- Creator:
- Navruzova, V. S. and Yuldasheva, N. Sh
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- nádory děložního čípku--patologie--terapie, imunohistochemie, staging nádorů, biopsie, metastázy nádorů, chemoterapie adjuvantní, radioterapie, nádorový supresorový protein p53--metabolismus, výsledek terapie, and lidé
- Language:
- English
- Description:
- To improve the results of radiotherapy for cervical cancer used local and systemic radiomodification drugs. Materials and methods: 1984 patients with locally advanced cervical cancer (2b 3a stage), which at one stage of complex treatment by a course indoarterial of regional longterm polychemotherapy (EARDPHT) mode: methotrexate 50 mg/m2, the first 12 hours, fluorouracil 1000 mg/m2, over the next 12 hours and cisplatin 100 mg/m2, for 48 hours, 2 stage surgical treatment in the volume expanding hysterectomy 3 type (modification of Wertheim Meigs). Results: The results of treatment of locally cervical cancer using VADRPHT, depending on the unilateral and bilateral tumor invasion in parametrial tissue showed that under unilateral lesion of parametrium results of treatment were higher than for the bilateral involvement of parametrium. Medical pathomorphosis in tumors of different severity was observed in 86.9% of patients, metastasis to regional lymph nodes were detected in 36% of operated patients, and also studied the degree of therapeutic pathomorphosis in lymph nodes. There was revealed that the complete regression of tumors, 5 year survival rate is 98%, whereas in tumor regression of more than 50% of the original volume 78.5%, with stabilization of tumor no more than 58.4%. Conclusion: The study of molecularbiological parameters of the tumor cells show the effectiveness of conducted neoadvent indoarterial chemotherapy and play an important role in further treatment and prediction of disease., Navruzova V. S., Yuldasheva N. Sh., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
68. Tlymphocytes (CD3+HLA-DR+) in patients over 60 with mediterranean spotted fever
- Creator:
- Gospodinova, Margarita
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- marseillská horečka--metabolismus--patofyziologie, imunitní systém--fyziologie, antigeny CD3--fyziologie, imunita buněčná, antigeny CD--fyziologie--metabolismus, T-lymfocyty--fyziologie--metabolismus, HLA-DR antigeny, rickettsiové infekce--diagnóza, statistika jako téma, dospělí, lidé, lidé středního věku, and mladý dospělý
- Language:
- English
- Description:
- Mediterranean spotted fever (MSF) in Bulgaria shows increasing severity, especially in patients over sixty years. As T lymphocytes are the primary effector cells in MSF and are altered by the ageing process we aimed to specify the changes in their numbers in elderly patients. We performed a clinicoepidemiological study, haematological and biochemical analysis of 132 patients of 60+ and 30 patients between 19 and 57 years with MSF. We investigated the cell immunity of 20 patients of 60+ using immunofluocytometry. The control group consisted of 10 younger patients and 10 healthy individuals of 60+. MSF showed more unfavourable course in the elderly.We found T-lymphocytes depletion in all patients with MSF. Activated T lymphocytes were increased in elderly patients with MSF. We found significant differences between the number of activated T lymphocytes in elderly patients and healthy elderly persons. The observed T-lymphocytes depletion in MSF corresponded to the disease severity. The increase in the activated T lymphocytes in patients over 60 years contributes to an adequate immune response., Margarita Gospodinova, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
69. To the question of carrying out of reconstructively - regenerative operations patients with colo- and ileo-stomy
- Creator:
- Isakulov, T. U., Mamatkulov, Sh. М, Rahmanov, S.T., and Matkarimov, S. R.
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- zavedení chirurgických vývodů, pooperační období, předoperační období, výsledek terapie, statistika jako téma, kolostomie, ileostomie, and lidé
- Language:
- English
- Description:
- The article analyses a surgical treatment of 506 patients taking inpatient treatment in the Center for colon proctology. All the patients underwent a comprehensive examination including radiological and tool test methods in addition to conventional clinical and laboratory ones. On the basis of the complex study, indications, volume and terms of surgery performance were determined. Performance of preand postoperative management of patients is substantiated in details. Postoperatively, 28 (5.5%) had postoperative wound pyesis in the region of the previous colostomy. In the postoperative period 2 (0.4%) deaths of patients were caused with peritonitis which occurred due to incompetence of anastomosis sutures. Rehabilitation of stomed patients is one of challenges in colorectal surgery. Positive results treatment can be obtained only at carrying out of a comprehensive outpatient and inpatient preoperative preparation including recommendations in diet, colostome care, hydrogymnastics of the disconnected part of the intestine and prevention of infectious complications., Isakulov T. U., Mamatkulov Sh. М., Rahmanov S.T., Matkarimov S. R., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
70. Ultrazvuková diagnostika maternice v šestonedelí
- Creator:
- Dosedla, Erik and Calda, Pavel
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, přehledy, and TEXT
- Subject:
- lidé, ženské pohlaví, dospělí, uterus--fyziologie--ultrasonografie, poporodní období--fyziologie, poruchy v puerperiu--ultrasonografie, porod, císařský řez, ultrasonografie--metody, poporodní krvácení--prevence a kontrola--ultrasonografie, placenta zadržená--ultrasonografie, břišní stěna--ultrasonografie, pooperační komplikace--ultrasonografie, and exsudáty a transudáty--ultrasonografie
- Language:
- Czech, Slovak, and English
- Description:
- Ultrazvukové vyšetrenie maternice po pôrode zahŕňa niektoré špecifiká, ktoré vyplývajú z rýchlo sa meniacich rozmerov maternice, ale aj compliance pacientky vo včasnom šestonedelí. Pri riešení popôrodných komplikácií je potrebné poznať normálny ultrazvukový nález, dynamické zmeny maternice v priebehu šestonedelia, aby sme vedeli lepšie rozpoznať patologický priebeh od normálneho priebehu šestonedelia. Klinický význam ultrazvukového posúdenia veľkosti maternice ako aj oblasti jazvy po cisárskom reze v priebehu šestonedelia doteraz nie je dostatočne popísaný. Prehľadový článok rozoberá špecifiká ultrazvukovej diagnostiky po vaginálnom pôrode a cisárskom reze. Autori článku prezentujú jednoduchú techniku vyšetrenia maternice po pôrode., Ultrasound examination of the uterus after delivery includes some features which result from rapidly changing dimensions of the uterus, but also patient compliance in the early puerperium. In dealing with postpartum complications is necessary to know the normal ultrasound findings, the dynamic changes in the uterus during the puerperium, so we can better recognize the pathological process during the normal puerperium. The clinical significance of ultrasound assessment of uterine size and the scar after Cesarean section during the puerperium have not been yet sufficiently described. Review article discusses the specifics of diagnostic ultrasound following vaginal delivery and Cesarean section. Authors of the article presents a simple technique of the uterus examination after childbirth., Erik Dosedla, Pavel Calda, and Literatura 42
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public