Historically, the main focus of the study of housing in advanced economies has been on houses that meet the accommodation needs of households: houses as the main residence of families. In recent decades there has been the growth in the numbers of houses used for purposes other than as a main residence, for example in the forms of the recent global spread of Airbnb and of foreign engagement in housing as an investment tool; alongside a set of ‘for housing’ houses (FHH) another, overlapping, set of ‘not for housing’ houses (NFHH) is emerging. The present paper begins by identifying four types of NFHH, and considers the significance of their growth. It argues that while the NFHH sector is relatively small it has large impacts, and these are such that they challenge housing researchers and policy makers to develop additional ways of looking at housing systems.
Homeownership has been in decline in a number of developed societies since the early 2000s driven, primarily, by declining entry among younger households who have been increasingly pushed into the rental sector. This trend has been associated with a growing intergenerational divide, or even conflict, and the emergence of ‘Generation Rent’. This paper explores the conditions surrounding diminishing access to owner-occupation among new households with a focus on the historic maturation of homeownership sectors, the restructuring of the political economy (financialization) around housing wealth and the inter-cohort dynamics surrounding the accumulation and transfer of housing wealth. The paper takes an international perspective drawing on evidence from two parallel, but contrasting cases: Japan and the UK. The analysis illustrates the interrelatedness of interand intra-generational inequalities, with the former reinforcing the latter. It also focuses on the role of families as both a moderator of generational inequity at the micro level as well as an enhancer of socioeconomic inequalities overall.
The residualisation of social housing sectors requires housing managers to intensify social management activities aimed at promoting tenants’ wellbeing and social cohesion. This paper discusses the implementation of such activities in the Italian public housing sector. It juxtaposes the vision conceptualised at the policy level with the daily activities of housing managers in practice on the ground and highlights the gaps between policy goals and realities of tenants’ involvement. While social management activities are expected to contribute to breaking the vicious circle of financial, technical, and social decline that has long affected public housing estates, the short timeframe of the planned interventions raises the question of the potential for structural change.
This article explores the trajectory of so-called guaranteed social housing in the Czech Republic as an example of penetrating financial instruments into the public policy realm. The project, promoted by the government’s Agency for Social Inclusion, was intended to encourage private landlords to rent their properties to people in need through commercial insurance against the risk of rent defaults. Using policy documents, media and interviews with governmental officers, the article describes the performative strength of financial instruments in the sphere traditionally occupied by the welfare state. In financialisation literature, the proliferation of financial instruments is often described as a one-way process in which these instruments colonise public domains. However, the empirical case discussed in the article shows that this process is much more complex and contingent, and financial instruments are not used as the best option but rather as a last resort in a situation marked by weak policies.
(Pro)renin receptor (PRR) contributes to regulating many physiological and pathological processes; however, the role of PRR-mediated signaling pathways in myocardial ischemia/reperfusion injury (IRI) remains unclear. In this study, we used an in vitro model of hypoxia/reoxygenation (H/R) to mimic IRI and carried out PRR knockdown by siRNA and PRR overexpression using cDNA in H9c2 cells. Cell proliferation activity was examined by MTT and Cell Counting Kit-8 (CCK-8) assays. Apoptosis-related factors, autophagy markers and β-catenin pathway activity were assessed by real-time PCR and western blotting. After 24 h of hypoxia followed by 2 h of reoxygenation, the expression levels of PRR, LC3B-I/II, Beclin1, cleaved caspase-3, cleaved caspase-9 and Bax were upregulated, suggesting that apoptosis and autophagy were increased in H9c2 cells. Contrary to the effects of PRR downregulation, the overexpression of PRR inhibited proliferation, induced apoptosis, increased the expression of pro-apoptotic factors and autophagy markers, and promoted activation of the β-catenin pathway. Furthermore, all these effects were reversed by treatment with the β-catenin antagonist DKK-1. Thus, we concluded that PRR activation can trigger H/R-induced apoptosis and autophagy in H9c2 cells through the β-catenin signaling pathway, which may provide new therapeutic targets for the prevention and treatment of myocardial IRI.
The adrenal glands produce significant amounts of steroid hormones and their metabolites, with various levels of androgenic activities. Until recently, the androgenic potency of these adrenal-derived compounds were not well known, but some recent studies have shown that the production of 11-oxoand 11β-hydroxy-derived testosterone and dihydrotestosterone evidently have high androgenic activity. This fact has clinical importance, for instance, in various types of congenital adrenal hyperplasia with androgenization or polycystic ovarian syndrome, and laboratory determinations of these substances could help to better evaluate the total androgen pressure in patients with these disorders. Another area of concern is the treatment of prostate cancer with androgen deprivation, which loses effectiveness after a certain time. The concurrent blocking of the secretion of adrenal C19-steroids, whether using corticoids or adrenostatics, could increase the effectiveness of androgen-deprivation therapy., Luboslav Stárka, Michaela Dušková, Jana Vítků., and Obsahuje bibliografii
a1_Patients with chronic kidney disease (CKD) have an increased risk of premature mortality, mainly due to cardiovascular causes. The association between hemodialysis and accelerated atherosclerosis has long been described. The ankle-brachial index (ABI) is a surrogate marker of atherosclerosis and recent studies indicate its utility as a predictor of future cardiovascular disease and all-cause mortality. The clinical implications of ABI cut-points are not well defined in patients with CKD. Echocardiography is the most widely used imaging method for cardiac evaluation. Structural and functional myocardial abnormalities are common in patients with CKD due to pressure and volume overload as well as non-hemodynamic factors associated with CKD. Our study aimed to identify markers of subclinical cardiovascular risk assessed using ABI and 2D and 3D echocardiographic parameters evaluating left ventricular (LV) structure and function in patients with end-stage renal disease (ESRD) (patients undergoing dialysis), patients after kidney transplantation and non-ESRD patients (control). In ESRD, particularly in hemodialysis patients, changes in cardiac structure, rather than function, seems to be more pronounced. 3D echocardiography appears to be more sensitive than 2D echocardiography in the assessment of myocardial structure and function in CKD patients. Particularly 3D derived end-diastolic volume and 3D derived LV mass indexed for body surface appears to deteriorate in dialyzed and transplanted patients. In 2D echocardiography, myocardial mass represented by left ventricular mass/body surface area index (LVMI) appears to be a more sensitive marker of cardiac structural changes, compared to relative wall thickness (RWT), left ventricle and diastolic diameter index (LVEDDI) and left atrial volume index (LAVI)., a2_We observed a generally favorable impact of kidney transplantation on cardiac structure and function; however, the differences were non-significant. The improvement seems to be more pronounced in cardiac function parameters, peak early diastolic velocity/average peak early diastolic velocity of mitral valve annulus (E/e´), 3D left ventricle ejection fraction (LV EF) and global longitudinal strain (GLS). We conclude that ABI is not an appropriate screening test to determine the cardiovascular risk in patients with ESRD., Magdaléna Kovářová, Zuzana Žilinská, Ján Páleš, Zuzana Kužmová, Andrea Gažová, Juraj Smaha, Martin Kužma, Peter Jackuliak, Viera Štvrtinová, Ján Kyselovič, Juraj Payer., and Obsahuje bibliografii
In the marine ecological system, the prime role of water management and durability of an ecosystem is being played by the vegetation patches. The vegetation patches in open channels can significantly affect the flow velocity, discharge capacity and hinder energy fluxes, which ultimately helps in controlling catastrophic floods. In this study, the numerical simulation for turbulent flow properties, i.e. velocity distribution, Reynolds stresses and Turbulent Intensities (TI) near the circular vegetation patches with progressively increasing density, were performed using the computational fluid dynamics (CFD) code ANSYS FLUENT. For examination of the turbulent flow features in the presence of circular patches with variable densities, Reynolds averaged Navier-Stokes equations, and Reynolds stress model (RSM) were employed. The numerical investigation was performed in the presence of in-line emergent and submerged patches having variable vegetation density in the downstream direction. Two of the cases were investigated with three circular patches having a clear gap to patch diameter ratio of La/D = 1 (where La is the clear spacing between the vegetation patches and D is the diameter of the circular patch), and the other two cases were analyzed with two patches having a clear gap ratio of La/D = 3. The case with a clear gap ratio (La/D = 3) showed 10.6% and 153% inflation in the magnitude of longitudinal velocity at the downstream of the sparse patch (aD = 0.8) and upstream of the dense patch (aD = 3.54), respectively (where aD is the flow blockage, in which “a” represents the patch frontal area and “D” represents the patch diameter). The velocity was reduced to 94% for emergent and 99% for submerged vegetation due to successive increase in vegetation density made by introducing a middle patch which reduced the clear gap ratio (La/D = 1). For La/D = 1, the longitudinal velocities at depth z = 15cm were increased by 319% than at depth z = 6cm at the downstream of the dense patch (aD = 3.54). Whereas it was observed to 365% higher in the case of La/D = 3. The magnitude of turbulent characteristics was observed 36% higher for submerged vegetation cases having a clear gap ratio of La/D = 1. The successive increase in the patch density reduced the Reynolds stresses, turbulent kinetic energy and turbulent intensities significantly within the gap region. The major reduction in the flow velocities and turbulent properties in the gaps provides a stable environment for aquatic ecosystems nourishment and fosters sediment deposition, and supports further vegetation growth.
In the rat model, 6-hydroxydopamine (6-OHDA) known as a selective catecholaminergic neurotoxin used chiefly in modeling Parkinson's disease (PD). Continuous aerobic exercise and curcumin supplementations could play a vital role in neuroprotection. This study aimed to explore the neuroprotective roles of regular aerobic exercise and curcumin during PD. For this, rats were treated as follows for 8 consecutive weeks (5 d in a week): For this, animals were orally treated with curcumin (50 ml/kg) alone or in combination with aerobic exercise. Compared with a control group, induction of PD by 6-OHDA increased the amount of α-synuclein protein and malondialdehyde levels and decreased the number of substantia nigra neurons, total antioxidant capacity, and glutathione peroxidase activity in brain tissue. All these changes were abolished by the administration of curcumin with aerobic exercise treatments. Activity behavioral tests also confirmed the above-mentioned results by increasing the rod test time and the number of rotations due to apomorphine injection. Histopathology assays mimic the antioxidant activity and behavioral observations. Combined curcumin with aerobic exercise treatments is potentially an effective strategy for modifying the dopaminergic neuron dysfunction in 6-OHDA-induced rats modeling PD via dual inhibiting oxidative stress indices and regulating behavioral tasks.
The multicoloured Asian ladybird Harmonia axyridis is an invasive insect that can negatively influence biodiversity and human economy in invaded areas. According to the enemy release hypothesis, invasive alien species are often little affected by parasites and other enemies. We studied the prevalence of common parasites of insects infesting and infecting H. axyridis in NW Poland. A large sample of 2351 individuals was collected and divided into two groups: 1180 beetles were dissected and examined for the presence of eugregarines, nematodes and Laboulbeniales fungi, and 751 were checked for phoretic mites. Our results show that H. axyridis is indeed parasitized infrequently. The prevalence of eugregarines and nematodes was very low (1.5% and 0.4%, respectively). No specimens of Laboulbeniales or phoretic mites were found. Our study indicates that in NW Poland H. axyridis is rarely infested or infected by parasites. This paper reports for the first time the infection of H. axyridis by the eugregarine Gregarina barbarara., Kryzstof Dudek, Paweł Sienkiewicz, Dariusz J. Gwiazdowicz, Piotr Tryjanowski., and Obsahuje bibliografii
Accurate survey methods are required for any wildlife research to yield reliable population data. This constraint finds significance in amphibian research that involves a highly threatened group of animals with a large proportion of cryptic species not easily detected by conventional survey methods. Across a growing spectrum of zoology research, survey outcomes are benefitting from the efficacy of scent detection dogs in assisting with species detection. We investigated the ability of a scent detection dog to locate and identify traces of giant bullfrog, Pyxicephalus adspersus scent and investigate methods of preserving frog scent for use in subsequent conditioning training of dogs. The scent detection dog was able to detect 100,000 times diluted scent with 87% sensitivity and 84% efficacy. High specificity (98,6%) was also achieved while presented with the challenge of detecting P. adspersus scent amid that of other frog species. Detection sensitivity was negatively correlated with scent preservation time but yielded the highest sensitivity for samples that were preserved as skin swabs stored at 4 °C and diluted shortly before use. Conservationists, scientists, and customs officials alike can benefit from scent detection dog detection of amphibians through enhanced sample acquisition rates with reduced collection biases.
Twenty eight species of winter-active Heleomyzidae were collected during a long-term study in Poland. More than 130 samples of insects, including Heleomyzidae, were collected from the surface of snow in lowland and mountain areas using a semi-quantitative method. Lowland and mountain assemblages of Heleomyzidae recorded on snow were quite different. Heleomyza modesta (Meigen, 1835) and Scoliocentra (Leriola) brachypterna (Loew, 1873) dominated in the mountains, Tephrochlamys rufiventris (Meigen, 1830) mainly in the lowlands and Heteromyza rotundicornis (Zetterstedt, 1846) was common in both habitats. Heleomyzidae were found on snow during the whole period of snow cover, but the catches peaked from late November to the beginning of February. In late winter and early spring the occurrence of heleomyzids on snow decreased. Most individuals were active on snow at air temperatures between -2 and +2.5°C. A checklist of 78 winter active European Heleomyzidae is presented. Helomyza nivalis Wahlgren, 1918 is herein considered as a new junior synonym of Helomyza caesia Meigen, 1830, syn. n., Agnieszka Soszyńska-Maj, Andrzej J. Woźnica., and Obsahuje bibliografii
Representatives of Ligophorus Euzet et Suriano, 1977 were found on the gills of Mugil liza Valenciennes caught in southern Brazil. They were identified as Ligophorus uruguayense Failla Siquier et Ostrowski de Núñez, 2009 and Ligophorus saladensis Marcotegui et Martorelli, 2009, even though specific identification proved to be difficult due to inconsistencies in some diagnostic features reported for these two species. Therefore, a combined morphological and molecular approach was used to critically review the validity of these species, by means of phase contrast and confocal fluorescence microscopical examination of sclerotised hard parts, and assessing the genetic divergence between L. saladensis, L. uruguayense and their congeners using rDNA sequences. The main morphological differences between the two species relate to the shape of the accessory piece of the penis and the median process of the ventral bar. The accessory piece in L. uruguayense is shorter than in L. saladensis, has a cylindrical, convex upper lobe and straight lower lobe (vs with the distal tip of the lower lobe turning away from the upper lobe in the latter species). The ventral bar has a V-shaped anterior median part in L. uruguayense (vs U-shaped in L. saladensis). The two species are suggested to be part of a species complex together with L. mediterraneus Sarabeev, Balbuena et Euzet, 2005. We recommend to generalise such comparative assessment of species of Ligophorus for a reliable picture of the diversity and diversification mechanisms within the genus, and to make full use of its potential as an additional marker for mullet taxonomy and systematics., Natalia C. Marchiori, Antoine Pariselle, Joaber Pereira Jr., Jean-François Agnèse, Jean-Dominique Durand, Maarten P.M. Vanhove., and Obsahuje bibliografii
Obtaining reliable estimates of population abundance is of utmost importance for wildlife research and management. To this aim, camera-traps are increasingly used, as this method has the advantage of being noninvasive and allows for continuous monitoring. Camera traps can be used to estimate abundance in combination with traditional capture-recapture techniques, as well as with estimators that do not require marked individuals. Here, we investigated the use of camera-based mark-recapture methods applied to an Alpine marmot (Marmota marmota) population in the Paneveggio-Pale di San Martino Natural Park (eastern Italian Alps). We compared abundance estimates derived from a traditional capture-mark-recapture (CMR) framework and camera trap mark-resight (CTMR) over three consecutive years. CMR models estimated a population size of n = 19 individuals (95% CI = 18-27), n = 15 (14-22) and n = 24 (22-32) in 2019, 2020 and 2021 respectively. CTMR returned an estimated population size of n = 24 (95% CI = 18-30), n = 20 (17-24) and n = 22 (21-24) for the same years. The difference between the estimate of these two methods was significant only in 2020, with CMR returning a lower estimate than CTMR (95% CI = –9.4-–0.6). This difference was not significant for 2019 (95% CI = –10.9-0.9) and 2021 (95% CI = –1.8-5.9). Based on our results, the use of CTMR techniques is promising in the estimation of absolute population size of marmots, and the estimator was slightly more precise than CMR. Further studies are needed to evaluate the effectiveness of CTMR with reduced capture effort.
We provide here a general introduction on chlorophyll (Chl) a fluorescence, then we present our measurements on fast (< 1 s) induction curves (the so-called OJIP transients) on dark-adapted intact leaves of Arabidopsis thaliana, under five different light intensities [in the range of ~ 500 to ~ 3,000 µmol(photons) m‒2 s‒1] using two different instruments: Handy PEA (Hansatech Instruments, UK; excitation light, 650 nm) and FluorPen (model FP-110; Photon Systems Instruments, The Czech Republic; excitation light, 470 nm). We then discuss the observed differences in the OJIP curves, as well as in Fo (F20μs, F50μs, or the extrapolated Ft→0), FP (the peak), and the ratios FP/Fo, and Fv (= FP ‒ Fo)/FP in terms of differences in excitation light intensity and absorptance (or absorbance) of the excitation light by the leaves, and other factors, as well as the data available in the literature. We suggest that such measurements be accompanied, in the future, by parallel measurements on Chl a fluorescence imaging, an area pioneered by Hartmut K. Lichtenthaler., B. Padhi, G. Chauhan, D. Kandoi, A. Stirbet, B. C. Tripathy, G. Govindjee., and Obsahuje bibliografické odkazy
Variable rate technology (VRT) in nutrient management has been developed in order to apply crop inputs according to the required amount of fertilizers. Meteorological conditions rarely differ within one field; however, differences in soil conditions responding to precipitation or evaporation results within field variations. These variations in soil properties such as moisture content, evapotranspiration ability, etc. requires site-specific treatments for the produced crops. There is an ongoing debate among experts on how to define management zones as well as how to define the required amount of fertilizers for phosphorus and nitrogen replenishment for winter wheat (Triticum aestivum L.) production. For management zone delineation, vegetation based or soil based data collection is applied, where various sensor technology or remote sensing is in help for the farmers. and The objective of the study reported in this paper was to investigate the effect of soil moisture data derived from Sentinel-2 satellite images moisture index and variable rate phosphorus and nitrogen fertilizer by means of variable rate application (VRA) in winter wheat in Mezőföld, Hungary. Satellite based moisture index variance at the time of sowing has been derived, calculated and later used for data comparison. Data for selected points showed strong correlation (R2 = 0.8056; n = 6) between moisture index and yield, however generally for the whole field correlation does not appear. Vegetation monitoring has been carried out by means of NDVI data calculation. On the field level, as indicated earlier neither moisture index values at sowing nor vegetation index data was sufficient to determine yield. Winter wheat production based on VRA treatment resulted significant increase in harvested crop: 5.07 t/h in 2013 compared to 8.9 t/ha in 2018. Uniformly managed (control) areas provided similar yield as VRA treated areas (8.82 and 8.9 t/ha, respectively); however, the input fertilizer was reduced by 108 kg/ha N and increased by 37 kg/ha P.
A key to genera of South American Deltocephalini Dallas, 1870 based on adult males is presented. Two new genera, each based on a single new species from Argentina are described and illustrated: Corrientesia gen. n. based on type species C. ochrescens sp. n. and Salnogia gen. n. based on type species S. fletcheri sp. n. A new species of Graminella DeLong, 1936, G. schrocki sp. n. from Argentina is also described and illustrated. Graminella stelliger (Berg, 1884) equals Fusanus acristylus Cheng, 1980, syn. n. A new combination, Limpica pallida (Linnavuori & DeLong, 1979) comb. n., transferred from Reventazonia Linnavuori, 1959, is also proposed. Quaziptus Kramer, 1965, is returned from Paralimnini Distant, 1908 to Deltocephalini Dallas, 1870., Yani Duan, Christopher H. Dietrich., and Obsahuje bibliografii
The Northern pine processionary moth, Thaumetopoea pinivora (Treitschke, 1834) shows a highly scattered distribution with fragmented populations across Europe. A previous study exploring the postglacial history of T. pinivora defined it as a cold-tolerant relict species and concluded that a progressive reduction of suitable habitats after the postglacial expansion from refugia in the southern Iberian peninsula best explained the distribution and genetic structure of populations of this species. However, recent records, both by us and others, challenge this view. Surprisingly, some of the newly found populations from southern Spain use black pine, Pinus nigra J.F. Arnold as a host plant despite the fact that the typical host of the species, Scots pine, Pinus sylvestris L. occurs in the area. We provide genetic data for one of these recently found southern populations where the larvae feed on P. nigra, and compare this with previously published data on individuals collected on P. sylvestris. This data reveals that populations from different host trees are no more genetically differentiated than populations sharing the same host plant. The findings of a wider diet breadth open the way to widen the search for the still unidentified glacial refugium of T. pinivora, and as such may contribute to a better understanding about how the species has spread across Europe., José A. Hódar, Anna Cassel-Lundhagen, Andrea Battisti, Stig Larsson., and Obsahuje bibliografii
People spend a large part of their awake time at work, which can have a huge impact on their life satisfaction. Scholars have found that job satisfaction influences life satisfaction, but the role of work alienation is little studied. While work alienation reportedly diminishes life satisfaction, just how job satisfaction relates with these two constructs has not yet been clarified. Currently, the role of labor union membership is an underestimated aspect of this relationship. Although the relationship between union membership and job satisfaction has been variously studied, its relationship with other variables (e.g., work alienation and life satisfaction) remains less investigated. To fill this gap, the authors examined the influence of work alienation on job and life satisfaction in relation to belonging or not to a public administration workers’ union. Self-report questionnaire responses (N=479) indicated a negative relationship between work alienation and job satisfaction and a negative influence on overall quality of life. The relationship between work alienation and life satisfaction, however, was moderated by union membership. Union memberships mitigated the negative relationship between work alienation and life satisfaction and may be considered a protective factor for workers’ quality of life. and Lidé tráví hodně svého času v práci, což může mít velký dopad na jejich životní spokojenost. Bylo zjištěno, že spokojenost s prací ovlivňuje spokojenost se životem, ale role práce byla málo zkoumána. Zatímco bylo zjištěno, že odcizení snižuje životní spokojenost, musí být ještě zkoumáno, jak spokojenost s prací souvisí s těmito dvěma konstrukty. V současné době je role členství v odborech podceňovaným aspektem tohoto vztahu. Ačkoli byl vztah mezi členstvím v odborech a spokojeností s prací zkoumán mnohokrát, vztah s jinými proměnnými (např. pracovní odcizení a spokojenost se životem) byl studován méně. Proto autoři zkoumali dopad pracovního odcizení na spokojenost s prací a životní spokojenost ve vztahu k členství v odborech pracovníků veřejné správy. Odpovědi na sebehodnotící dotazník (N = 479) naznačily negativní vztah mezi pracovním odcizením a spokojeností s prací a negativní vliv na celkovou kvalitu života. Vztah mezi pracovním odcizením a životní spokojeností byl však zmírněn členstvím v odborech. Členství v odborech zmírnilo negativní vztah mezi mezi pracovním odcizením a životní spokojeností a lze je považovat za ochranný faktor pro kvalitu života zaměstnanců.