A mobile exhibition, German Science Train, which is organized by the Max Planck Society as part of the Year of Science 2009, takes the public on a research voyage! The idea is to show different aspects of science with an eye to the future. In 12 converted train cars, visitors can dive into different subjects: from cosmology to particle physics, nanotechnology and brain research to applied and industrial research in production, agriculture, energy, environment and mobility. The exhibition is making stops throughout Germany until December. and Luděk Svoboda.
Přibližně 520 dní trvá let na Mars a zpět - 520 dní trvala simulace takového letu a bezmála stejnou dobu i příprava a vydání publikace Psychologického ústavu AV ČR „Mars-500: Fakta a postřehy ze simulovaného letu na rudou planetu“, která se tímto ojedinělým experimentem zabývá. and Marina Hužvárová.
Vědci z experimentu NOvA koncem března tohoto roku úspěšně otestovli první plně funkční části tzv. vzdáleného detektoru. Po jejím zapnutí poprvé zaznamenali dráhy částic kosmického záření prolétajících aktivní částí detektoru. V polovině letošního roku bude spuštěn neutrinový svazek a detektory experimentu.NOvA začnou pátrat po interakcích neutrin s cílem určit jejich některé vlastnosti., Karel Soustružník [et al.]., and Obsahuje seznam literatury
Disturbance of capillary perfusions due to leukocyte adhesion, disseminated intravascular coagulat ion, tissue edema is critical components in the pathophysiology of sepsis. Alterations in brain microcirculation during sepsis are not clearly understood. The aim of this study is to gain an improved understanding of alterations through direct visualization of brain microcirculations in an experimental endotoxemi a using intravital microscopy (IVM). Endotoxemia was induced in Lewis rats with Lipopolysaccharide (LPS, 15 mg/kg i.v.). The dura mater was removed via a cranial window to expose the pial vessels on the brain surface. Using fluorescence dyes, plasma extravasation of pial venous vessels and leukocyte-endothelial interaction were visualized by intravital microscopy 4 h after LPS administration. Plasma cytokine levels of IL1-β, IL-6, IFN-γ, TNF-α and KC/GRO were evaluated after IVM. A sign ificant plasma extravasation of the pial venous vessels was found in endotoxemia rats compared to control animals. In addition , a significantly increased number of leukocytes adherent to the pial venous endothelium was observed in septic animals. Endotoxemia also induced a significant elevation of plasma cytokine levels of IL1-β, IL-6, IFN-γ, TNF-α and KC/GRO. Endotoxemia increased permeability in the brain pial vessels accompanied by an increase of leukocyte-endothelium interactions and an increase of inflammatory cytokines in the plasma., J. Zhou ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
Spontaneous depolarization similar to that from the sinus node was documented from the myocardial sleeves of pulmonary veins (PV) after isolation procedures. It was then hypothesized that sinus node-like tissue is present in the PVs of humans. Based on a number of features, the myocar dium of myocardial sleeves (MS) is highly arrhythmogenic. Membrane potentials originating from MS are invariably recordable at the PVs ostia in patients with atrial fibrillation (AF) and delayed conduction around the PVs ostia may play a role in re-e ntry process responsible for the initiation and maintenance of AF. Diagnostic and therapeutic evidence of premature atrial beats induced in MS of PVs and resulting in launch of AF was detected by 3D electroanatomic method of monophasic action potential (MAP). MAP recording plays an important role in a di rect view of human myocardial electrophysiology under both physiological and pathological conditions. Its crucial importance lies in the fact that it enables the study of the action potential of myocardial cell in vivo and, therefore, the study of the dynamic relation of this potential with all the organism variables. The knowledge of pathological MAPs from PV myocardial sleeves can help us to confirm a diagnosis when finding the similar action potential morphology. MAP can be also used to evaluate the therap eutic efficiency of vagal nerves suppression, radiofrequency ablation or other treatment procedures in PVs myocardial sleeves as well as for post- treatment following up., O. Kittnar, S.-G. Yang, M. Mlček., and Obsahuje bibliografii a bibliografické odkazy