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22712. The isolated photosystem two reaction centre reveals details of the molecular processes of photoinhibition
- Creator:
- Barber, J.
- Format:
- Type:
- model:internalpart and TEXT
- Language:
- Multiple languages
- Description:
- Under certain conditions the isolated reaction centre (RC) of photosystem 2 (PS 2) ís highly vulnerahle to photoinduced damage. With no added secondary electron acceptors or donors tíďs damage is due to singlet oxygen generated by the P680 triplet. This triplet is formed by recombination of the radical pair PóSO+Pheo' and Ihe photoinduced damage only occurs under aerobic conditions. When an electron acceptor is present, the degradation of pigments and the Dl and D2 proteins is due to formation of P680+ and secondary oxidation processes. Under the latter but not the former condition, characteristic pattems of degradation firagments of the Dl and D2 proteins are observed. In particular 24 and 17 kDa breakdown firagments of Dl are obtained while the D2 protein yields firagments having molecular masses of 29 and 21 kDa. Experiments involving the use of antibodies, radiophosphate and speciííc proteolytic digestion indicate that all four firagments contain the C-terminal portions of their mature proteins. These findings indicate that the proteolytic cleavage sites are positioned on the lumenal side of the membrane, particularly in the region spanning transmembrane helices I and II. Related studies on the 24 lď)a Dl protein fragment generated in vivo using Synechocystis sp. PCC 6803 by photoinhibitory treatment give the same conclusion for this firagment. Such a conclusion seems to contrast with the previous suggestion that the initial cleavage of Dl protein associated with its degradatíon and tumover occurs on the outer side of membrane in the region spanning transmembrane helices IV and V.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
22713. The Kaliningrad earthquakes of September 21, 2004
- Creator:
- Wiejacz, Paweł
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Geologie. Meteorologie. Klimatologie, seizmicita, seismicity, baltské země, Baltic countries, local seismicity, baltic region, hypocenter location, source mechanism, 7, and 551
- Language:
- English
- Description:
- The earthquakes of magnitudes ML=5.0 and 5.3 in the Kaliningrad enclave of Russia on September 21, 2004 were unexpected in a very low-seismicity area. The earthquakes caused minor damage in the Kaliningrad enclave, in northern Poland and in southwestern Lithuania, and macroseismic intensities of 6-7 (EMS) close to the epicenters. The earthquakes were felt up to 800 km distance. The events have been located under the central-northern part of the Sambia Penninsula at 16 and 20 km depth. Their source mechanism has been found to be a right lateral strike slip on a direction parallel to the edge of the Fennoscandian Shield and the East European Craton. The possible cause of the earthquakes is discussed. With the glaciotectonic cause unlikely, it seems the earthquakes evidence tectonic patterns, possibly resulting from stress propagating all across Europe from the Mediterranean region. Historical information seems to evidence past seismic activity in the region, which together with the 2004 earthquakes show the need to reassess seismic hazard in the area., Paweł Wiejacz., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
22714. The Kautsky effect: 60 years of chlorophyli fluorescence índuction kinetics
- Creator:
- Lichtenhaler, H. K.
- Format:
- Type:
- model:internalpart and TEXT
- Language:
- Multiple languages
- Description:
- The detection of the Kautsky effect, i.e. the chlorophyll (Chl) fluorescence índuction kínetics induced in the dark-adapted leaves because of a sudden irradiation, by Hans Kautsky and his students is reviewed here on the occasíon of the 60* anniversary of this CW fluorescence transient discovery and oftBě 100* birth anniversary of Hans Kautsky in 1991.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
22715. The labile iron pool in monocytes reflects the activity of the atherosclerotic process in men with chronic cardiovascular disease
- Creator:
- Riško, P., Jan Pláteník, Buchal, R., Jana Potočková, and Kraml, P. J.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, záněty, inflammations, iron overload, monocytes, arterial stiffness, 14, and 612
- Language:
- English
- Description:
- The study investigates the relationship between the labile iron pool (LIP) in circulating monocytes and markers of iron metabolism, inflammation, oxidative stress, endothelial dysfunction and arterial elasticity in patients with chronic cardiovascular disease and in healthy volunteers. The patie nts with a history of CVEs had significantly higher LIP values tha n did the control group (1.94± 0.46 μM vs. 1.62 ±0.49 μM, p=0.02). Except for the leukocyte number (WBCs), the groups did not differ in other inflammatory markers (CRPus, CD 163, MPO, MMP-1). Similarly, there were no differences in the markers of endothelial dysfunction (ICAM, VCAM, E-selectin, vWF). The CVE group had higher pulse pressures, levels of markers of impaired arterial elasticity (AI, Young's modulus, pulsatility, stiffness index), I MT values and ABI values. The LIP concentration was significantly correlated with the transferrin receptor⁄ferritin ratio, hepcidin levels, VFT content and the ABI and ET values. Patients with a history of CVE have significantly higher concentrations of ir on in their intracellular LIP in circulating monocytes than do healthy controls. The independent and significant correlation of LIP with markers of the progression of atherosclerosis and arterial stiffness suggests LIP as a possible novel marker of atheros clerotic activity., P. Riško, J. Pláteník, R. Buchal, J. Potočková, P. J. Kraml., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
22716. The Labyrinth of the world and the paradise of the heart
- Creator:
- Jan Amos Komenský and František Lützow
- Publisher:
- Swan Sonnenschein & Co., Lim.
- Format:
- print, svazek, and 347 stran.
- Type:
- model:monograph and TEXT
- Subject:
- Česká próza, Komenský, Jan Amos, 1592-1670, 17. století, baroko, překlady do angličtiny, baroque, translations into English, 821.162.3-3, 82"15/17", 811.111’25, and 25
- Language:
- English and Czech
- Description:
- by John Amos Komensky (Comenius) ; edited and translated by Lützow. and KČSN (sg. S-N)
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
22717. The late miocene pelitic siltstone of the Ishim Formation (Southwestern Siberia): mineralogical and geomechanical characterization and prospects for further use
- Creator:
- Konstantinov, Alexander O, Smirnov, Pavel V, Kuzmina, Olga B, Khazina, Irina V, Batalin, Georgii A, and Gareev, Bulat I
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- sedimentární horniny, plniva, sedimentary rocks, fillers (materials), Sibiř západní (Rusko), Siberia, Western (Russia), late miocene, pelitic siltstone, mineral addiction, 7, and 551
- Language:
- English
- Description:
- a1_The Miocene Ishim Formation is characterized by a considerable distribution area within the southwestern Siberia. These deposits are highly dispersed and are composed mainly of angular quartz grains of aleuritic and pelitic fractions. The study of the Ishim Formation is of interest both for investigating the origin of the sediments, and for justifying these rocks as a new type of mineral raw material for the local construction materials industry. This paper presents the results of first complex studies of the Ishim Formation deposits from two outcrops Masali and Bigila. The studies included determination of the particle size distribution on the laser particle analyzer, semiquantitative determination of the mineral composition (X-ray diffraction analysis), as well as, determination of contents of sesquioxides (X-ray fluorescence analysis), rare and trace elements (Inductively Coupled Plasma Mass Spectrometry) and measurement of specific surface area. The most representative samples were chosen for petrographic studies. In certain extent these deposits are characterized by quite high degree of homogeneity of the mineral, chemical, and granulometric compositions. The main component is SiO2 (about 70 %); other most important components are Al2O3 (about 14 %) and Fe2O3 (2-5 %). At the same time, deposits of the upper part of the Ishim Formation are depleted in CaO, MnO, MgO, TiO2, and P2O5. This is probably due to the fact that the proportion of clayey minerals in the upper part of the formation is lower than that in the lower one. The contents of trace elements in the Ishim Formation are lower or close to their clarke values in the Earth's crust. This is with the exception of such elements as Eu, Tb, Cr, and Sb, which form a strong anomaly and, to a lesser extent, a number of other elements that is probably related to the tectonic setting during the period of sedimentation., a2_The CIA values vary from 68-70 in the lower unit of the Ishim Formation at the transition to the sandy facies to 75-80 in the upper one, which indicates a moderate weathering of rocks. The results obtained testify to the fact that these deposits were formed under the conditions of degrading shallow water bodies. A distinct geomorphological confinement to boundaries of the Neogene river paleovalleys, continuity, high dispersion and, predominantly, quartz composition allow us to consider these deposits as a promising type of filler for construction materials industry., Alexander O. Konstantinov, Pavel V. Smirnov, Olga B. Kuzmina, Irina V. Khazina, Georgii A. Batalin and Bulat I. Gareev., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
22718. The Libechov minipig as a large animal model for preclinical research in Huntington’s disease – thoughts and perspectives
- Creator:
- Schramke, S., Schubert, R., Frank, F., Wirsig, M., Fels, M., Kemper, N., Schuldenzucker, V., and Reilmann, R.
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, práce podpořená grantem, and TEXT
- Subject:
- zvířata, zvířata geneticky modifikovaná, prasata, prasata miniaturní, modely u zvířat, preklinické hodnocení léčiv, Huntingtonova nemoc, chov, bydlení zvířat, časové faktory, mozek--anatomie a histologie, velikost orgánu, experimenty na zvířatech, etika výzkumu, and sekvenční homologie
- Language:
- Czech and English
- Description:
- Large animal models to explore the safety and tolerability of novel therapeutic approaches for Huntington’s disease (HD) are in exploration to achieve higher translational reliability in future studies. Recently, a Libechov minipig has been established as one new transgenic (Tg) large animal model for HD. We here discuss the advantages and limitations in using this model in HD with regards to breeding, housing, handling, and with respect to homology to humans and ethical considerations. A group of TgHD and wild type (WT) female minipigs (n = 36) was used to gain first evidence about abovementioned aspects. It is concluded that Libechov minipigs may fulfill an important role to bridge the gap between rodents and non‑human primates in the translation to humans. and S. Schramke, R. Schubert, F. Frank, M. Wirsig, M. Fels, N. Kemper, V. Schuldenzucker, R. Reilmann
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
22719. The Liberating Power of Exiled Laughter: Gender, Caricature, and the Antifascist Movement in the Pre-War Czechoslovakia. The Case of Simplicus
- Creator:
- Pachmanová, Martina
- Format:
- Type:
- model:internalpart and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
22720. The life and times of Master John Hus
- Creator:
- František Lützow
- Publisher:
- J.M. Dent & Co.
- Format:
- print, svazek, and ix, 398 stran : portréty.
- Type:
- model:monograph and TEXT
- Subject:
- Dějiny Česka a Slovenska, Biografie, Hus, Jan, asi 1371-1415, dějiny, reformace, křesťanští teologové, křesťanští reformátoři, Česko, 94(437), 27-9"14/15", 27-337, (437.3), (092), 8, and 929
- Language:
- English
- Description:
- by the Count Lützow., KČSN - S-D 292, Obsahuje rejstřík, and Obsahuje české věnování od autora - S-D 292
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public