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20902. Simulace tlakových změn musculus levator ani při nepravidelnostech polohy a držení plodu v průběhu vaginálního porodu a vaginální extrakční operace – 3D MRI based model
- Creator:
- Krofta, Ladislav, Havelková, L., Krčmář, Michal, Urbánková, Iva, Gojiš, Ondřej, Hynčík, Luděk, and Feyereisl, Jaroslav
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, abstrakt z konference, and TEXT
- Language:
- Czech
- Description:
- Krofta L., Havelková L., Krčmář M., Urbánková I., Gojiš O., Hynčík L., Feyereisl J.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
20903. Simulace zobrazení povrchů pomocí bezkontaktní metody AFM
- Creator:
- Kalousek, Radek, Škoda, David, Lopour, Filip, and Šikola, Tomáš
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- fyzika povrchů pevných látek, mikroskopie atomárních sil, křemík, surfaces (physics), atomic force microscopy, silicon, 6, and 53
- Language:
- Czech
- Description:
- Příspěvek se zabývá otázkou interakčních sil mezi hrotem sondy a studovaným povrchem při měření profilu povrchu pomocí bezkontaktní mikroskopie atomárních sil (AFM), které jsou zodpovědné za atomární rozlišení. Využitím kombinace dalekodosahových přitažlivých van der Waalsových sil a krátkodosahových odpudivých sil jsou prezentovány simulace zobrazovacích principů. Toto modelování umožňuje získat obrázky vybraných povrchů (např. Si) a diskutovat limity rozlišení metody., Radek Kalousek, David Škoda, Filip Lopour, Tomáš Šikola., and Obsahuje seznam literatury
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20904. Simulácia elementárnych procesov atmosféry Titanu v elektrických výbojoch
- Creator:
- Horváth, Gabriel, Országh, J., Matejčík, Štefan, Zahoran, M., and Mason, N. J.
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- Titan (měsíc), zemská atmosféra, elektrické výboje, Titan (Satellite), atmosphere of Earth, electric discharges, 6, and 523/524
- Language:
- Czech
- Description:
- Atmosféra Titanu je zložená najmä z dusíka a metánu. Je tu pomerne častá elektrická aktivita v podobě atmosférických výbojov. Tieto podmienky pripomínajú stav atmosféry Zeme v jej počiatkoch. Je zaujímavé skúmať, ako v danom prostredí vznikajú základné organické molekuly, které sú stavebnými prvkami živých organizmov. Zaoberáme sa simuláciami procesov vedúcich ku tvorbe takýchto zlúčenin. Za prostredie vhodné pre simuláciu sme zvolili jednosmerný korónový výboj horiaci v zmesi dusíka a metánu. Výsledky ukazujú, že produktami výboja sú také zlúčeniny, ktoré boli detegované aj v atmosfére Titanu., G. Horváth, J. Országh, Š. Matejčík, M. Zahoran, N. J. Mason., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20905. Simulation of biomass cofiring with coal by adition of cellulose and lignin
- Creator:
- Šušák, Petr, Silvie Vallová, and Juraj Leško
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Geologie. Meteorologie. Klimatologie, lignin, thermogravimetry, coal cofiring, cellulose, 7, and 551
- Language:
- English
- Description:
- Oxidation kinetics of celulose, lignin, brown coal, and their mixtures were investigated. Using non-linear regression method kinetic parameters from thermogravimetric curves were calculated for oxidation of volatile matter and fixed carbon (char). The presence of the cellulose in the mixture affects the rate constant of lignin and brown coal oxidation which was determined by means of Arrhenius plots., Petr Šušák, Silvie Vallová and Juraj Leško., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20906. Simulation of PSII-operating efficiency from chlorophyll fluorescence in response to light and temperature in chrysanthemum (Dendranthema grandiflora) using a multilayer leaf model
- Creator:
- Janka, E., Körner, O, Rosenqvist, E., and Ottosen, C.-O.
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- skleníky, fotosyntéza, greenhouses, photosynthesis, extrémní klima, extreme climate, monitor, paradermal layer, 2, and 581
- Language:
- Multiple languages
- Description:
- Chlorophyll fluorescence serves as a proxy photosynthesis measure under different climatic conditions. The objective of the study was to predict PSII quantum yield using greenhouse microclimate data to monitor plant conditions under various climates. Multilayer leaf model was applied to model fluorescence emission from actinic light-adapted (F') leaves, maximum fluorescence from light-adapted (Fm') leaves, PSII-operating efficiency (Fq'/Fm'), and electron transport rate (ETR). A linear function was used to approximate F' from several measurements under constant and variable light conditions. Model performance was evaluated by comparing the differences between the root mean square error (RMSE) and mean square error (MSE) of observed and predicted values. The model exhibited predictive success for Fq'/Fm' and ETR under different temperature and light conditions with lower RMSE and MSE. However, prediction of F' and Fm' was poor due to a weak relationship under constant (R2 = 0.48) and variable (R2 = 0.35) light., E. Janka, O. Körner, E. Rosenqvist, C.-O. Ottosen., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20907. Simultaneous decrease of plasma obestatin and ghrelin levels after a high-carbohydrate breakfast in healthy women
- Creator:
- Dana Sedláčková, Ivana Dostálová, Vojtěch Hainer, Beranová, L., Hana Kvasničková, Martin Hill, Martin Haluzík, and Jara Nedvídková
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, endokrinologie, biochemie, endocrinology, biochemistry, obestatin, total ghrelin, acyl ghrelin, desacyl ghrelin, carbohydrate breakfast, 14, and 612
- Language:
- English
- Description:
- Ghrelin is a gut peptide produced mainly by stomach, well known to induce appetite stimulatory actions. Obestatin, a recently identified peptide derived from preproghrelin, was initially described to antagonize stimulatory effect of ghrelin on food intake. The postprandial response of obestatin and its relationship with ghrelin in humans remains unknown. We therefore investigated the postprandial response of obestatin and total ghrelin, acyl and desacyl ghrelin and neuropeptide Y (NPY) to a high-carbohydrate breakfast (1 604 kJ) in eight healthy women (age: 24.2±0.82 years; BMI 21.6±0.61 kg/m2). Blood samples were collected before the meal, and 30, 60, 90, 120 and 150 min after the breakfast consumption. Postprandial plasma obestatin concentrations significantly decreased compared with preprandial levels as well as total ghrelin concentrations and reached the lowest values 90 and 120 min after the meal consumption, respectively (p 0.05). Plasma acyl and desacyl ghrelin concentrations decreased after the breakfast and reached lowest values in 30 and 60 min, respectively (p<0.05). Plasma NPY concentrations were lower than preprandial levels 90 and 150 min after consuming breakfast (p<0.05). In conclusion, we demonstrated in healthy young women that plasma obestatin concentrations decrease similarly to ghrelin after a high-carbohydrate breakfast., D. Sedláčková, I. Dostálová, V. Hainer, L. Beranová, H. Kvasničková, M. Hill, M. Haluzík, J. Nedvídková., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20908. Simultaneous measurement of thermoluminescence emission and of fluorescence Fq
- Creator:
- Miranda, T. and Ducruet, J. M.
- Format:
- Type:
- model:internalpart and TEXT
- Language:
- Multiple languages
- Description:
- The chlorophyll fluorescence Fo, excited by polsed ultra-weak blue radiatíon, and thermoluminescence (TL) were recorded in ďie same sample. Temperature-dependent variations of the fluorescence yield influenced ťhe TL emission.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20909. Simvastatin alleviates myocardial contractile dysfunction and lethal ischemic injury in rat heart independent of cholesterol-lowering effects
- Creator:
- Adriana Adameová, Anna Harčárová, Jana Matejíková, Dezider Pancza, Magdaléna Kuželová, Slávka Čarnická, Peter Švec, Monika Barteková, Ján Styk, and Ravingerová, T.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, cholesterol, statiny, srdce, ischemie, statins, heart, ischemia, pleiotropic effects, 14, and 612
- Language:
- English
- Description:
- a1_Statins, the inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are most frequently used drugs in the prevention of coronary artery disease due to their cholesterol- lowering activity. However, it is not exactly known whether these effects of statins or those independent of cholesterol decrease account for the protection ag ainst myocardial ischemia- reperfusion (I/R) injury. In this study, we investigated the effect of 5-day treatment with simvastatin (10 mg/kg) in Langendorff- perfused hearts of healthy control (C) and diabetic- hypercholesterolemic (D-H; strept ozotocin + high fat-cholesterol diet, 5 days) rats subjected to 30-min global ischemia followed by 40-min reperfusion for the examination of postischemic contractile dysfunction and reperfusion-induced ventricular arrhythmias or to 30-min (left anterior descending) coronary artery occlusion and 2-h reperfusion for the infarct size determination (IS; tetrazolium stai ning). Postischemic recovery of left ventricular developed pressu re (LVDP) in animals with D-H was improved by simvastatin therapy (62.7±18.2 % of preischemic values vs. 30.3±5.7 % in the untreated D-H; P<0.05), similar to the values in the simvastatin-treated C group, which were 2.5-fold higher than those in the untreated C group. No ventricular fibrillation occurred in the simvastatin-treated C and D-H animals during reperf usion. Likewise, simvastatin shortened the duration of ventri cular tachycardia (10.2±8.1 s and 57.8±29.3 s in C and D-H vs. 143.6±28.6 s and 159.3±44.3 s in untreated C and D-H, respectively, both P<0.05). The decreased arrhythmogenesis in the simvastatin-treated groups correlated with the limitation of IS (in % of risk area) by 66 % and 62 % in C and D-H groups, respectively. However, simvastatin treatment decreased plasma cholesterol levels neither in the D-H animals nor in C., a2_The results indicate that other effects of statins (independent of cholesterol lowering) are involved in the improvement of contractile recovery and attenuation of lethal I/R injury in both, healthy and diseased individuals., A. Adameová, A. Harčárová, J. Matejíková, D. Pancza, M. Kuželová, S. Čarnická, P. Švec, M. Barteková, J. Styk, T. Ravingerová., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
20910. Simvastatin decreased coenzyme Q in the left ventricle and skeletal muscle but not in the brain and liver in L-NAME-induced hypertension
- Creator:
- Jarmila Kucharská, Anna Gvozdjáková, and Fedor Šimko
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, hypertenze, hypertension, simvastatin, NO-deficient hypertension, tissue coenzyme Q, L_NAME, 14, and 612
- Language:
- English
- Description:
- Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (statins) have been proven to reduce effectively cholesterol level and morbidity and mortality in patients with coronary heart disease and/or dyslipoproteinemia. Statins inhibit synthesis of mevalonate, a precursor of both cholesterol and coenzyme Q (CoQ). Inhibited biosynthesis of CoQ may be involved in some undesirable actions of statins. We investigated the effect of simvastatin on tissue CoQ concentrations in the rat model of NO-deficient hypertension induced by chronic L-NAME administration. Male Wistar rats were treated daily for 6 weeks with L-NAME (40 mg/kg) or with simvastatin (10 mg/kg), another group received simultaneously L-NAME and simvastatin in the same doses. Coenzyme Q9 and Q10 concentrations were analyzed by high performance liquid chromatography. L-NAME and simvastatin alone had no effect on CoQ concentrations. However, simultaneous application of L-NAME and simvastatin significantly decreased concentrations of both CoQ homologues in the left ventricle and slightly decreased CoQ9 concentration in the skeletal muscle. No effect was observed on CoQ level in the liver and brain. We conclude that the administration of simvastatin under the condition of NO-deficiency reduced the level of CoQ in the heart and skeletal muscle what may participate in adverse effect of statins under certain clinical conditions., J. Kucharská, A. Gvozdjáková, F. Šimko., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public