The Union of Czech Mathematicians and Physicists celebrated the 150th anniversary of its foundation. On the occasion of this anniversary on March 28, 2012, the Union at Karolinum, the seat of the Charles University, a festive ceremony, attended by outstanding personalities headed by the President of the Czech Republic Vaclav Klaus. The Union was founded in 1862 as the Association for Free Lectures in Mathematics and Physics. From the beginning, its goal was the improvement of the teaching physics and mathematics at schools on all levels and of all types and further, to support and promote the development of those sciences. As a consequence of patriotic efforts, the Association was enlarged in 1869 into the Union of Czech Mathematicians and Physicists. In the early 1950s, the Union had to transfer its property to the newly established Czechoslovak Academy of Sciences (CSAV) and it became a learned society affiliated with CSAV. The mathematical part of its library became the basis of the library of the Mathematical Institute of CSAV, and is located there at present. Today, the Union has about 2,800 members. The Union itself, or in collaboration with universities and research institutes, organizes national as well as international conferences, symposia, seminars, and Summer or Winter schools. The Union follows the teaching of mathematics and physics in schools and proposes improvements. It encourages talented students and participates in the organization of the Mathematical and Physical Olympiad and other student competitions. Czech Post has issued a stamp commemorating the 150"i Anniversary of the Foundation of the Union of Czech Mathematicians and Physicists. and Martina Bečvárová.
The Velvet Revolution was a non-violent uprising in Czechoslovakia that saw the overthrow of the Communist government. On November 17, 1989, police suppressed a peaceful student demonstration in Prague. Among the protesters were many young employees of Czechoslovak Academy of Sciences. Based on the November events, civil forums were created at worksplaces. In consequences of the political evolvement, some of the compromised directors from institutes left their positions and during the following six months all directors had to be evaluated. Scientific committies began to form. On November 6, 1989, the entire presidium of ČSAV resigned and December 12, the Chamber of elected representatives of ČSAV was established. This organ became a carrier of fundamental changes, for example the first Czech science foundation was set up and proposals for evaluation of the institutes formed. The new organization structures of Academy were created. and Antonín Kostlán.
Cíl: Zjistit přínos 18F-fluorocholinového PET/ CT (18F-FCH PET/CT) pro cílenou biopsii prostaty u pacientů s opakovaně negativními biopsiemi a trvajícím podezřením na přítomnost karcinomu prostaty. Soubor pacientů a metoda: Od ledna 2013 do května 2015 jsme provedli 18-F-FCH PET/CT cholinové PET CT vyšetření u 30 pacientů. Indikačním kritériem bylo PSA nad 10 ng/ml a prodělání více než tři biopsií prostaty, včetně biopsie saturační. Pokud to bylo možné, pak pacienti předem prodělali šestitýdenní kůru ATB terapie Doxycyklinem 100mg 2x denně k eliminaci zánětu, a tím možným falešně pozitivním nálezům na 18F-FCH PET/CT. Poté bylo provedeno PET/CT vyšetření a následně s odstupem byla provedena cílená biopsie ložisek popsaných na 18F-FCH PET/CT. Cílená biopsie byla provedena pod sonografickou kontrolou transrektálně za pomoci kognitivní fúze PET/CT obrazu s real-time sonografickým záznamem. Byly odebírány jen vzorky z ložisek popsaných na PET/CT. Výsledky: Od ledna 2013 do května 2015 absolvovalo 18F-FCH PET/CT 30 pacientů. Průměrný věk pacientů byl 66 let v rozmezí 57–75 let. U 14 z nich jsme potvrdili karcinom prostaty, což činí 46% záchyt ve skupině rebiopsií. Všichni tito pacienti měli Gleasonovo skóre vyšší než sedm a PSA vyšší než 20 ng/ml. Závěr: V našem souboru jsme prokázali přínos 18F-FCH PET/CT u pacientů s opakovaně negativními biopsiemi a pokračující elevací PSA, u kterých nebyl karcinom prostaty standardním způsobem detekován. Ložisko vyznačené pomocí 18F-cholinufluorocholinu umožnilo cílenou biopsii pod sonografickou kontrolou. V současnosti není jednoznačné doporučení, jak postupovat u pacientů, u kterých máme opakovaně negativní biopsie prostaty a trvá podezření na přítomnost karcinomu. Využití 18F-FCH PET/CT se jeví jako jedna z mož- ností., Aim: The aim of the study was to determine the benefits of 18F-fluorocholine PET/CT in patients with repeated negative biopsies and continued suspicion of prostate carcinoma. Material and methods: 18F-fluorocholine PET/CT (18F-FCH PET/CT) was performed with 30 patients from January 2013 until May 2015. Indication criteria were PSA above 10 ng/ml and three biopsies. If possible patients underwent six weeks treatment of antibiotic therapy with Doxycyclin 100mg twice per day to eliminate inflammation and possible false findings in PET/CT. Then PET/CT was performed with following targeted biopsy of focus from 18F-FCH PET/CT. Targeted biopsy was done under the sonographic transrectal control with the help of cognitive fusion PET/CT image with real-time sonography. Only samples from centers identified with PET/CT were taken. Results: From January 2013 until May 2015 30 patients underwent 18F-FCH PET/CT. Average age of patients was 66 years (57–75 years). We confirmed prostate cancer in 14 of them which is 46 % success in rebiopsy group. All these patients had Gleason score above seven and PSA higher than 20 ng/ml. Conclusions: We have shown in our sample the benefits of 18F-cholinFCH PET/CT in patients with repeated negative biopsies and continued PSA elevation, where prostate carcinoma was not detected in standard biopsies. The use of 18F-FCH PET/CT seems promising in diagnostic of prostate cancer where 18F-fluorocholine can be found also in slow growing cells of majority of prostate carcinoma. Using this method we can diagnose also tumors, which are located outside of typical areas in the peripheral zone and therefore can be missed even in repeated biopsies., Šárka Kudláčková, Milan Král, Pavel Koranda, Vladimír Študent, and Literatura