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31522. Pure filters and stable topology on BL-algebra
- Creator:
- Eslami, Esfandiar and Haghani, Farhad Kh.
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- BL-algebra, prime filters, maximal filters, pure filters, and stable topology
- Language:
- English
- Description:
- In this paper we introduce stable topology and F-topology on the set of all prime filters of a BL-algebra A and show that the set of all prime filters of A, namely Spec(A) with the stable topology is a compact space but not T0. Then by means of stable topology, we define and study pure filters of a BL-algebra A and obtain a one to one correspondence between pure filters of A and closed subsets of Max(A), the set of all maximal filters of A, as a subspace of Spec(A). We also show that for any filter F of BL-algebra A if σ(F)=F then U(F) is stable and F is a pure filter of A, where σ(F)={a∈A|y∧z=0 for some z∈F and y∈a⊥} and U(F)={P∈ Spec(A) |F⊈P}.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
31523. Pure states on Jordan algebras
- Creator:
- Hamhalter, Jan
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- JB algebras, C*lgebras, pure states, and state space independence of Jordan algebras
- Language:
- English
- Description:
- We prove that a pure state on a ȁlgebra or a JB algebra is a unique extension of some pure state on a singly generated subalgebra if and only if its left kernel has a countable approximative unit. In particular, any pure state on a separable JB algebra is uniquely determined by some singly generated subalgebra. By contrast, only normal pure states on JBW algebras are determined by singly generated subalgebras, which provides a new characterization of normal pure states. As an application we contribute to the extension problem and strengthen the hitherto known results on independence of operator algebras arising in the quantum field theory.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
31524. Pure subgroups
- Creator:
- Bican, Ladislav
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- torsion-free abelian groups, pure subgroup, and P-pure subgroup
- Language:
- English
- Description:
- Let λ be an infinite cardinal. Set λ0 = λ, define λi+1 = 2λi for every i = 0, 1,..., take µ as the first cardinal with λi < µ, i = 0, 1,... and put κ = (µℵ0 ) +. If F is a torsion-free group of cardinality at least κ and K is its subgroup such that F/K is torsion and |F/K| ≤ λ, then K contains a non-zero subgroup pure in F. This generalizes the result from a previous paper dealing with F/K p-primary.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
31525. Puri philosophi no est theologizare. Reflections on Method in John Wyclif's and his Bohemian Followers' Discussions of the Eternity of the World /
- Creator:
- Campi, Luigi
- Type:
- text and studie
- Subject:
- Filozofie, Wycliffe, John,, Hus, Jan,, Jeroným Pražský,, filozofie, teologie, světové dějiny středověku (do r. 1492), české země 1306-1526, filozofie, filozofové, and teologie, ikonografie, zbožnost, hagiografie
- Language:
- English
- Rights:
- unknown
31526. Purification and characterization of a novel thermoacidophilic and thermostable α-mannosidase from the digestive fluid of oil palm weevil Rhynchophorus palmarum (Coleoptera: Curculionidae) larvae
- Creator:
- Bédikou, Micaël, Ahi, Pascal, Koné, Martial, Faulet, Betty, Gonnety, Jean, Kouamé, Patricie, and Niamké, Sébastien
- Type:
- article, model:article, and TEXT
- Subject:
- a-mannosidase, thermoacidophilic, thermostable, oil palm weevil, Rhynchophorus palmarum, and Curculionidae
- Language:
- English
- Description:
- An extracellular α-mannosidase with unusual properties was purified from the digestive fluid of oil palm weevil (Rhynchophorus palmarum Linnaeus) larvae using ammonium sulphate saturation, size exclusion and anion-exchange chromatography. The enzyme named RpltM is thermoacidophilic, thermostable and behaves like lysosomal α-mannosidase (EC 3.2.1.24). The molecular weight, Km value, optimum reaction temperature and pH are 108-112 kDa, 0.36 mM, 65°C and 4.5, respectively. Zn2+ enhanced whereas Cu2+, Sodium dodecyl sulphate, swainsonine and 1,4-dideoxy-1,4-iminomannitol strongly inhibited its hydrolytic activity. The enzyme was stable for 25 min at 65°C and retained 70% of its initial activity after 60 min. At 70°C, around 60% of this activity was conserved after 25 min. RpltM retained more than 90% of its activity over a pH range of 4.2 to 5.0 and remained fully active in the presence of detergents such as nonidet P-40, triton X-100, polyoxyethylen-10-oleyl ether (up to 1%, w/v), dithiothreitol and β-mercaptoethanol. The stability under these conditions is also better than that reported for other insect α-mannosidases. Thus, RpltM could be used as an important bioindustrial tool for removing mannose residues from oligosaccharides.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
31527. Purification and Properties of Ornithine Carbamoyltransferase from Loggerhead Turtle Liver
- Creator:
- Bellocco, E., Di Salvo, C., Lagan, G., Leuzzi, U., Tellone, E., Kotyk, A., and Galtieri, A.
- Format:
- print, bez média, and svazek
- Type:
- article, studie, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, Loggerhead turtle, Caretta caretta, Ornithine carbamoyltransferase, Enzyme kinetics, Enzyme thermostability, 14, and 612
- Language:
- English
- Description:
- Ornithine carbamoyltransferase has been purified from the liver of the loggerhead turtle Caretta caretta by a single-step procedure using chromatography on an affinity column to which the transition-state analogue, d-N-(phosphonoacetyl)- L-ornithine (d-PALO), was covalently bound. The procedure employed yielded an enzyme which was purified 373-fold and was judged to be homogeneous by nondenaturing and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). The enzyme showed a specific activity of 224. The molar mass of the C. caretta enzyme was approximately 112 kDa, the single band obtained by SDS-PAGE indicated a subunit molar mass of 39.5 kDa; hence, the enzyme is a trimer of identical subunits. It catalyzes an ordered sequential mechanism in which carbamoyl phosphate binds first, followed by L-ornithine. The Michaelis constants were 0.858 mM for L-ornithine and 0.22 mM for carbamoyl phosphate, the dissociation constant of the enzyme-carbamoyl phosphate complex was 0.50 mM., E. Bellocco, C. Di Salvo, G. Lagan, U. Leuzzi, E. Tellone, A. Kotyk, A. Galtieri., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
31528. Purified acetaminophen-glutathione conjugate is able to induce oxidative stress in rat liver mitochondria
- Creator:
- Tomáš Roušar, Nýdlová, E., Petr Česla, Pavla Křiváková, Otto Kučera, Patrik Pařík, and Zuzana Červinková
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, acetaminophen toxicity, glutathione, acetaminophenglutathione conjugate, 14, and 612
- Language:
- English
- Description:
- Acetaminophen overdose is the most often cause of acute liver injury. The toxic mechanism is linked to formation of an active metabolite that reacts with glutathione generating acetaminophen-glutathione conjugate (APAP-SG). This compound has been recognized to be non-toxic generally. Our preliminary results showed, however, that APAP-SG could possess a toxic effect too. Therefore, the aim of our study was to prepare, purify and to test possible toxicity of APAP-SG. We prepared APAP-SG using organic synthesis. The conjugate was purified by preparative HPLC and its structure was confirmed using mass spectrometry. Final purity of APAP-SG was >98 %. We estimated a toxic effect of APAP-SG in isolated rat liver mitochondria using a fluorescent ROS probe. We assessed ROS production in presence of complex I or complex II substrates. The increase of ROS-dependent fluorescence in presence of glutamate/malate was 104±13 % and 130±10 % in 1 mM and 5 mM APAP-SG, respectively, in comparison with controls. ROS production related to presence of complex II substrate was enhanced 4-times in APAP-SG (5 mM) treated mitochondria (compared to controls). We conclude, we proved our hypothesis that APAP-SG conjugate is able to induce a mitochondrial impairment leading to enhanced ROS production., T. Roušar, ... [et al.]., and Obsahuje seznam literatury
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
31529. Purinoceptors, renal microvascular function and hypertension
- Creator:
- Guan, Zhengrong, Makled, Mirhan N., and Inscho, Edward W.
- Format:
- počítač and online zdroj
- Type:
- model:article and TEXT
- Subject:
- ATP, renal autoregulation, inflammation, epithelial sodium channel, and reactive oxygen species
- Language:
- English
- Description:
- Proper renal blood flow (RBF) and glomerular filtration rate (GFR) are critical for maintaining normal blood pressure, kidney function and water and electrolyte homeostasis. The renal microvasculature expresses a multitude of receptors mediating vasodilation and vasoconstriction, which can influence glomerular blood flow and capillary pressure. Despite this, RBF and GFR remain quite stable when arterial pressure fluctuates because of the autoregulatory mechanism. ATP and adenosine participate in autoregulatory control of RBF and GFR via activation of two different purinoceptor families (P1 and P2). Purinoceptors are widely expressed in renal microvasculature and tubules. Emerging data show altered purinoceptor signaling in hypertension-associated kidney injury, diabetic nephropathy, sepsis, ischemia-reperfusion induced acute kidney injury and polycystic kidney disease. In this brief review, we highlight recent studies and new insights on purinoceptors regulating renal microvascular function and renal hemodynamics. We also address the mechanisms underlying renal microvascular injury and impaired renal autoregulation, focusing on purinoceptor signaling and hypertension-induced renal microvascular dysfunction. Interested readers are directed to several excellent and comprehensive reviews that recently covered the topics of renal autoregulation, and nucleotides in kidney function under physiological and pathophysiological conditions (Inscho 2009, Navar et al. 2008, Carlstrom et al. 2015, Vallon et al. 2020).
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
31530. Puritans and "The Dark Corners of the Land" /
- Creator:
- Hill, Christopher,
- Type:
- text and studie
- Subject:
- Dějiny britských ostrovů, dějiny náboženství, Velká Británie, církve, sekty, and světové dějiny 1492-1648
- Language:
- English
- Rights:
- unknown