Lokalita Kopčany byla v období 9. až 10. stol. pravděpodobně hlavním sídelním areálem ve slovenské části nivy řeky Moravy v širším zázemí hradiště Valy u Mikulčic. V blízkosti tamního kostela byli někdy ve 2. pol. 9. a v 1. pol. 10. stol. pohřbíváni příslušníci místní společenské elity. Část výbavy z těchto hrobů byla podrobena průzkumu zaměřenému na techniku a kvalitu řemeslného zpracování a na jakost užitých materiálů. Cílem bylo získat informace, které by napomáhaly ověřit vztah kopčanské nobility k centru mikulčické aglomerace. Bylo zjištěno, že sledované předměty (3 nože, sekera, 4 ostruhy a 4 šperky) mají kvalitu porovnatelnou s obdobnými nálezy z Mikulčic. Koresponduje to s předpokladem, že pocházejí ze stejných zdrojů, kterých využívala elita sídlící na moravské straně mikulčicko-kopčanské aglomerace. and In the 9th and 10th centuries located in Kopčany in the Slovak part of the Morava River basin was in all likelihood the main residential area in the hinterlands of the agglomeration near Mikulčice. Members of the local social elite were buried near the local church sometime in the second half of the 9th and first half of the 10th centuries. Several objects recovered from these graves were subjected to special research focused exclusively on the methods and quality of craftsmanship and the quality of materials. The goal was to obtain information that would help verify the relationship between the Kopčany nobility and the Mikulčice agglomeration. It was determined that the studied objects (3 knives, an axe, 4 spurs and 4 pieces of jewellery) are of a quality comparable to similar finds from Mikulčice which confirms the hypothesis that they come from the same sources used by the elite living on the Moravian side of the Mikulčice-Kopčany agglomeration.
Antiorthostatic hindlimb suspension (unloading) decreased the resting membrane potential (RMP) of skeletal muscle fibers in fast extensor digitorum longus (EDL) and slow soleus (SOL) muscle of the rat by about 10 % within 7 days and more. Inactivation of the membrane Na+,K+-pump by ouabain brought about similar depolarization as unloading. The increased sodium permeability of the membrane was excluded as the major cause of this depolarization by experiments in which TRIS was substituted for Na+ in the medium. On the other hand, the decrease in the electrogenic participation of the Na+,K+-pump is apparently one of the causes of RMP decrease during hypogravity, in EDL muscle in particular., O. Tyapkina ... [et al.]., and Obsahuje seznam literatury
We present the current state of complex circulatory dynamics model development based on Guyt on’s famous diagram. The aim is to provide an open-source model that will allow the simulation of a number of pathological conditions on a virtual patient including cardiac, respiratory, and kidney failure. The model will also simulate the therapeutic influence of various drugs, infusions of electrolytes, blood transfusion, etc. As a current result of implementation, we describe a co re model of human physiology targeting the systemic circulation, arterial pressure and body fluid regulation, including short- and long-term regulations. The model can be used for educational purposes and general reflection on physiological regulation in path ogenesis of various diseases., J. Kofránek, J. Rusz., and Obsahuje bibliografii