Let $(H,\alpha )$ be a monoidal Hom-Hopf algebra and $(A,\beta )$ a right $(H,\alpha )$-Hom-comodule algebra. We first introduce the notion of a relative Hom-Hopf module and prove that the functor $F $ from the category of relative Hom-Hopf modules to the category of right $(A, \beta )$-Hom-modules has a right adjoint. Furthermore, we prove a Maschke type theorem for the category of relative Hom-Hopf modules. In fact, we give necessary and sufficient conditions for the functor that forgets the $(H, \alpha )$-coaction to be separable. This leads to a generalized notion of integrals.
In this paper a model for the recovery of human and economic activities in a region, which underwent a serious disaster, is proposed. The model treats the case that the disaster region has an industrial collaboration with a non-disaster region in the production system and, especially, depends upon each other in technological development. The economic growth model is based on the classical theory of R. M. Solow (1956), and the full model is described as a nonlinear system of ordinary differential equations.
In this paper, we present a novel quantitative description of intracellular and t-tubular Ca2+ dynamics in a model of rat cardiac ventricular myocyte. In order to simulate recently published data, the model incorporates t-tubular and peripheral dyads and intracellular subspaces, segmentation of the t-tubular luminal volume, reformulation of the inactivation properties of t-tubular land peripheral L-type calcium current (ICa) and a description of exogenous Ca2q+ buffer function in the intracellular space. The model is used to explore activity-induced changes of ion concentration in the intracellular and t-tubular spaces and their role in excitation - contraction coupling in ventricular myocytes. and Obsahuje Appendix se seznamy literatury, užitých zkratek a symbolů
In this paper we show that the measure generated by the indefinite Henstock-Kurzweil integral is $F_{\sigma \delta }$ regular. As a result, we give a shorter proof of the measure-theoretic characterization of the Henstock-Kurzweil integral.
Short-winged (brachypterous) and long-winged (macropterous) adult females of Pyrrhocoris apterus (L.) originating from a Mediterranean population (Israel) were analyzed for their adipokinetic responses. The adipokinetic response, expressed as an increase of haemolymph lipids after injection of adipokinetic hormone from Locusta migratoria (Lom-AKH-I), was assessed in relation to age and dose of the hormone. We demonstrate in this study that the adipokinetic responses induced by bug's corpora cardiaca extract and Lom-AKH-I were dose-dependent for both brachypterous and macropterous females. Significant differences between the morphs were recorded for doses >= 0.25 corpora cardiaca equivalent (P < 0.01) and doses >= 0.25 pmol Lom-AKH-I (P < 0.05). The haemolymph lipid elevations induced in both morphs by 2 pmols Lom-AKH-I are comparable with that induced by crude extract of one pair of the bug's own corpora cardiaca. The age-dependent test showed much higher adipokinetic responses (P < 0.01) in macropterous females (>= 5 days old) than in the brachypterous females of the same age, when treated with 2 pmols Lom-AKH-I. Starting from day 7, the concentration of haemolymph lipids was also considerably higher (2.5-5 times) in macropterous females than in the brachypterous ones. The obtained data indicate that difference in mobilization of lipids between brachypterous and macropterous females is a geographically independent feature and represents a true wing morph characteristic of P. apterus., Dalibor Kodrík, Radomír Socha, and Lit
The general author‘s mesomechanical model with tensorial internal variables is applied to creep of steel 0,5Cr0,5Mo0,3V under different loading levels. It is shown that the creep process can be described by the mesomechanical model in its whole course up to rupture. However, the model parameters can be influenced at the very beginning by the application of the applied load if it is high enough to cause changes in the internal structure. This problem is specific for creep at high temperatures and significant differences in the loading levels (contrary to the small-strain plasticity studied usually at low temperatures, where the model parameters can be considered the same for different loadings). and Obsahuje seznam literatury
Steroid profiling helps various pathologies to be rapidly
diagnosed. Results from analyses investigating steroidogenic
pathways may be used as a tool for uncovering pathology
causations and proposals of new therapeutic approaches. The
purpose of this study was to address still underutilized application
of the advanced GC-MS/MS platform for the multicomponent
quantification of endogenous steroids. We developed and
validated a GC-MS/MS method for the quantification of
58 unconjugated steroids and 42 polar conjugates of steroids
(after hydrolysis) in human blood. The present method was
validated not only for blood of men and non-pregnant women
but also for blood of pregnant women and for mixed umbilical
cord blood. The spectrum of analytes includes common
hormones operating via nuclear receptors as well as other
bioactive substances like immunomodulatory and neuroactive
steroids. Our present results are comparable with those from our
previously published GC-MS method as well as the results of
others. The present method was extended for corticoids and
17α-hydroxylated 5α/β-reduced pregnanes, which are useful for
the investigation of alternative “backdoor” pathway. When
comparing the analytical characteristics of the present and
previous method, the first exhibit by far higher selectivity, and
generally higher sensitivity and better precision particularly for
17α-hydroxysteroids.