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2022. An evaluation of non-destructive methods to estimate total chlorophyll content
- Creator:
- Cassol, D., de Silva, F. S. P., Falqueto, A. R., and Bacarin, M. A.
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- Ceiba, Cucumis, Raphanus, and Zea
- Language:
- Multiple languages
- Description:
- The portable chlorophyll (Chl) meter (CL-01, Hansatech) has been successfully used for a rapid and direct estimation of total Chl content in the leaves of some crops. We compared CL-01 meter readings (Chl value) and Chl contents in leaves of Zea mays, Cucumis sativus, Raphanus sativus, and Ceiba speciosa. Chl index was linearly and positively correlated to Chl content in all the species. and D. Cassol ... [et al.].
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2023. An evaluation of rolling contact fatigue of metallic materials using acoustic emission method
- Creator:
- Nohál, Libor and Mazal, Pavel
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- acoustic emission, rolling contact fatigue, defect, bearing, and pitting
- Language:
- English
- Description:
- A major cause of a surface damage of the contact loading machine components (bearings, gears, cams etc.) is the rolling contact fatigue, Various methods of condition monitoring are used to detect damage of these components or specimens in the industry or during testing in laboratories. In the past decades, the acoustic emission technique has been developed into useful condition monitoring method. This paper is focused on the testing of rolling contact fatigue of the metallic materials using acoustic emission method. The methodology of testing, experimenal test-rig and preliminary results, are presented in this paper. It can be concluded, that acoustic emission technique can be applied for more accurate rolling contact fatique evaluation of material. and Obsahuje seznam literatury
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2024. An evaluation of the levels of 25-hydroxyvitamin D3 and bone turnover markers in professional football players and in physically inactive men
- Creator:
- Krzysztof Solarz, Kopeć, A., Pietraszewska, J., Majda, F., Słowińska-Lisowska, M., and Mędraś, M.
- Format:
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, vitamin D, fotbalisté, soccer players, bone turnover markers, football players, physical activity, 25(OH)D3, 14, and 612
- Language:
- English
- Description:
- Vitamin D is synthesised in the skin during exposure to sunlight and its fundamental roles are the regulation of calcium and phosphate metabolism and bone mineralisation. The aim of our study was to evaluate serum levels of 25-hydroxyvitamin D3 , PTH and bone turnover markers (P1NP, OC, β -CTx, OC/ β -CTx) and the intake of calcium and vitamin D in Polish Professional Football League (Ekstraklasa) players and in young men with a low level of physical activity. Fifty healthy men aged 19 to 34 years were included in the study. We showed that 25(OH)D3 and P1NP levels and OC/ β -CTx were higher in the group of professional football players than in the group of phys ically inactive men. The daily vitamin D and calcium intake in th e group of professional football players was also higher. We showed a significant relationship between 25(OH)D3 levels and body mass, body cell mass, total body water, fat-free mass, muscle mass, vitamin D and calcium intake. Optimum 25(OH)D3 levels were observed in a mere 16.7 % of the football players and vitamin D deficiency was observed in the physically inactive men. The level of physical activity, body composition, calcium and vitamin D intake and the duration of exposure to sunlight may significantly affect serum levels of 25(OH)D3 ., K. Solarz ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2025. An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells
- Creator:
- Zdeněk Dvořák, Radim Vrzal, Petr Pávek, and Jitka Ulrichová
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Biochemie. Molekulární biologie. Biofyzika, biochemie, buněčné signály, membránové receptory, xenobiotika, glukokortikoidy, genetická informace, biochemistry, cell signals, membrane receptors, xenobiotics, glucocorticoids, genetic information, dioxin, transcriptional control, 2, and 577
- Language:
- English
- Description:
- Aryl hydrocarbon receptor (AhR) and glucocorticoid receptor (GR) play crucial role in the regulation of drug metabolizing enzymes and in many essential physiological processes. Cellular signaling by these receptors shares several functional and regulatory features. Here we investigated regulatory cross-talk between these two receptors. Human hepatoma cells (HepG2) were the model of choice. We analyzed the effects of dexamethasone (DEX) and dioxin (TCDD) on i) expression of AhR and GRα mRNAs; ii) levels of AhR and GR proteins; iii) transcriptional activities of AhR and GR in reporter assays; iv) 7-ethoxyresorufin-O-deethylase activity (EROD). We found that both DEX and TCDD affected AhR and GR mRNAs expression, proteins levels and transcriptional activities in HepG2 cells. These effects on cellular signaling by AhR and GR comprised up-/down-regulation of gene expression and ligand-dependent protein degradation. We conclude that interactive regulatory cross-talk between GR and AhR receptors in HepG2 cells defines possible implications in physiology and drug metabolism. Future research should be focused on the investigation of AhR-GR cross-talk in various normal human cells and tissues both in vitro and in vivo., Z. Dvořák, R. Vrzal, P. Pávek, J. Ulrichová., and Obsahuje bibliografii a bibliigrafické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2026. An experimental, non-uremic rabbit model of peritoneal dialysis
- Creator:
- Zunic-Bozinovski, S., Lausevic, Z., Krstic, S., Jovanovic, N., Trbojevic-Stankovic, J., and Stojimirovic, B.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Patologie. Klinická medicína, experimentální medicína, peritoneální dialýza, králík, experimental medicine, peritoneal dialysis, Oryctolagus, experimental model, non-uremic rabbit, 14, and 616
- Language:
- English
- Description:
- Peritoneal dialysis (PD) is a well established method of depuration in uremic patients. Standard dialysis solutions currently in use are not biocompatible with the peritoneal membrane. Studying effects of dialysate on peritoneal membrane in humans is still a challenge. There is no consensus on the ideal experimental model so far. We, therefore, wanted to develop a new experimental non-uremic rabbit model of peritoneal dialysis, which would be practical, easy to conduct, not too costly, and convenient to investigate the long-term effect of dialysis fluids. The study was done on 17 healthy Chinchilla male and female rabbits, anesthetized with Thiopental in a dose of 0.5 mg/kg body mass. A catheter, specially made from Tro-soluset (Troge Medical GMBH, Hamburg, Germany) infusion system, was then surgically inserted and tunneled from animals' abdomen to their neck. The planned experimental procedure was 4 weeks of peritoneal dialysate instillation. The presented non-uremic rabbit model of peritoneal dialysis is relatively inexpensive, does not require sophisticated technology and was well tolerated by the animals. Complications such as peritonitis, dialysis fluid leakage, constipation and catheter obstruction were negligible. This model is reproducible and can be used to analyze the effects of different dialysis solutions on the rabbit peritoneal membrane., S. Zunic-Bozinovski, Z. Lausevic, S. Krstic, N. Jovanovic, J. Trbojevic-Stankovic, B. Stojimirovic., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2027. An ideal biological marker of Alzheimer's disease: dream or reality?
- Creator:
- Daniela Řípová and Anna Strunecká
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, Alzheimerova choroba, bílkoviny, recenze, Alzheimer's disease, proteins, reviews, biological peripheral marker, β-amyloid, 14, and 612
- Language:
- English
- Description:
- Senile dementia of Alzheimer´s type (AD) is commonly characterized as a neurodegenerative disorder, which exhibits gradual changes of consciousness, loss of memory, perception and orientation as well as loss of personality and intellect. AD prevalence increases dramatically with age and is the fourth cause of death in Europe and in the USA. Currently, there are no available biological markers, which gives clinicians no other alternative than to rely upon clinical diagnosis by exclusion. There is no assay of objective ante mortem biochemical phenomena that relate to the pathophysiology of this disease. The pathophysiology of AD is connected with alterations in neurotransmission, plaque formation, cytoskeletal abnormalities and disturbances of calcium homeostasis. The search for a test, which is non-invasive, simple, cheap and user-friendly, should be directed at accessible body fluids. Only abnormalities replicated in large series across different laboratories fulfilling the criteria for a biological marker are likely to be of relevance in diagnosing AD. To date, only the combination of cerebrospinal fluid t and Ab42 most closely approximate an ideal biomarker of Alzheimer´s disease. A short review on the role of biological markers in AD on the basis of the literature, contemporary knowledge and our own recent findings are presented., D. Řípová, A. Strunecká., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2028. An immunosuppressed rat model for evaluation of anti-Cryptosporidium activity of sinefungin
- Creator:
- Brasseur, P., Favennec, L., Leméteil, D., Roussel, F., and Ballet, J.J.
- Format:
- Type:
- model:internalpart and TEXT
- Subject:
- Cryptosporidium parvum, sinefungin, anti-cryptosporidial drug, rat model, and treatment
- Language:
- English
- Description:
- Cryptosporidium parvum causes life-threatening diarrhoea in immunocompromized, especially AIDS patients and the efficiency of proposed anti-cryptosporidial therapies is limited or doubtful. An immunosuppressed adult rat model of C. parvum infection was developed for screening molecules candidate for curative and preventive activity in human cryptosporidiosis. Among 31 drugs tested, lasalocid (2-10 mg/kg/24 h), and sinefungin (2-10 mg/kg/24 h), exhibited some activity against C. parvum infection. Oral sinefungin therapy resulted in a dose related suppression of oocysts shedding, which correlated with oocyst disappearance from ileum sections and was also efficient in preventing infection. Relapses were observed after discontinuation of curative sinefungin therapy, which suggests that the biliary tract, a major location and parasite reservoir which sustains persisting infection, was not cleared of parasites by the drug. Improved therapeutic procedures with sinefungin (or analogues) will result from current pharmacological studies.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2029. An Imperial Dream: The “Russification” of Sacral Architecture in the Polish Lands in the 19th Century
- Creator:
- Paszkiewicz, Piotr
- Format:
- Type:
- model:internalpart and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
2030. An improved classifier and transliterator of hand-written Palmyrene letters to Latin
- Creator:
- Hamplová, Adéla, Franc, David, and Veselý, Arnošt
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- artificial intelligence, classification, historical alphabets, mobilenet, and computer vision
- Language:
- English
- Description:
- This article presents the problem of improving the classifier of handwritten letters from historical alphabets, using letter classification algorithms and transliterating them to Latin. We apply it on Palmyrene alphabet, which is a complex alphabet with letters, some of which are very similar to each other. We created a mobile application for Palmyrene alphabet that is able to transliterate hand-written letters or letters that are given as photograph images. At first, the core of the application was based on MobileNet, but the classification results were not suitable enough. In this article, we suggest an improved, better performing convolutional neural network architecture for hand-written letter classifier used in our mobile application. Our suggested new convolutional neural network architecture shows an improvement in accuracy from 0.6893 to 0.9821 by 142% for hand-written model in comparison with the original MobileNet. Future plans are to improve the photographic model as well.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public