Bradykinin can enhance skeletal muscle glucose uptake (GU), and exercise increases both br adykinin production and muscle insulin sensitivity, but bradykinin’s relationship with post-exercise insulin action is uncertain. Our primary aim was to determine if the B2 receptor of bradykinin (B2R) is essential for the post- exercise increase in GU by insulin-stimulated mouse soleus muscles. Wildtype (WT) and B2 R knockout (B2RKO) mice were sedentary or performed 60 minutes of treadmill exercise. Isolated soleus muscles were incubated with [ 3 H]-2-deoxyglucose ±insulin (60 or 100 μ U/ml). GU tended to be greater for WT vs. B2RKO soleus with 60 μ U/ml insulin (P=0.166) and was significantly greater for muscles with 100 μ U/ml insulin (P<0.05). Both genotypes had significant exercise-induced reductions (P<0.05) in glycemia and insulinemia, and the decrements for glucose (~14 %) and insulin (~55 %) were similar between genotypes. GU tended to be greater for exercised vs. sedentary soleus with 60 μ U/ml insulin (P=0.063) and wa s significantly greater for muscles with 100 μ U/ml insulin (P<0.05). There were no significant interactions between genotype and exercise for blood glucose, plasma insulin or GU. These results indicate that the B2R is not essential for the exerci se-induced decrements in blood glucose or plasma insulin or for the post-exercise increase in GU by insulin-stimulated mouse soleus muscle., G. G. Schweitzer ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
In this study, the 2n = 58 chromosomal race of blind mole rats,
Nannospalax xanthodon, from the Erzincan province in Turkey was investigated. Conventional chromosome staining, Ag-NOR staining and C-banding analysis were carried out in the specimens studied. The karyotype included three small or medium-sized meta/submetacentric pairs and twenty-five acrocentric pairs of autosomes of gradually diminishing size (NFa = 62). C-heterochromatin regions were found in centromeric and pericentromeric areas or in short arms of some bi-armed autosomal pairs and in pericentromeric areas of a few acrocentric autosomes. The X chromosome had a centromeric C-positive band and the short arm of the Y chromosome appeared to be C-positively stained. The NORs were
localized in distal heterochromatin areas of the short arms of two pairs of biarmed and one pair of acrocentric autosomes. Within the 58 chromosome populations reported from Turkey, two groups can be recognized differing by the presence or absence of a large submetacentric autosomal pair. The populations possessing this marker chromosome occur in central and northern Anatolia, whereas populations form eastern Anatolia have no similar chromosome in their karyotype.
Field observations in the northwest of Naein (Central Iran zone) indicate various types of alteration products have extended into pyroclastic and volcanic units with Oligo- miocene age. It seems the Zefreh (with NW- SE trend) and Kachumesqal (with E-W trend) faults are effective factors in the formation of Neysian and Barzavand copper deposits respectively. Alteration in Barzavand copper deposit (with stratabound form) includes pyritization, propylitization, zeolitization, saussuritization, uralitization and silicification, while in Neysian (with oval form) include phyllic, advanced argillic, argillic and propylitic. Geochemical studies in Barzavand show the positive correlation between (La/Lu)N, (La/Yb)N and (La/Sm)N and CaO (r= 0.70 to 0.96) related to propylitization of host rock basalt and increase in pH of fluids responsible for mineralization that play important role in differentiation of lanthanides in study area. The Barzavand copper deposit has submarine volcanism, diagenesis, burial metamorphism and weathering stages during its evolution. Remarkable geochemical features in Neysian include high (La/Lu)N, Ba and Sr values than La, Ce and Y. It seems that extensive alteration occurred along with hypogene and supergene processes in Neysian. According to alteration properties, mineralogy and the whole-rock geochemistry, the Barzavand and Neysian copper deposits are most similar to Manto- type and porphyry copper deposits respectively.
The bathymetric range of 149 digenean species recorded deeper than 200 m, the approximate depth of the continental shelf/slope break, are presented in graphical form. It is found that only representatives of the four families Lepocreadiidae, Fellodistomidae, Derogenidae and Hemiuridae reach to abyssal regions (>4,000 m). Three other families, the Lecithasteridae, Zoogonidae and Opecoelidae, have truly deep-water forms reaching deeper than 3,000 m. Bathymetric data are available for the Acanthocolpidae, Accacoeliidae, Bucephalidae, Cryptogonimidae, Faustulidae, Gorgoderidae, Monorchiidae and Sanguinicolidae showing that they reach deeper than 200 m. No bathymetric data are available for the members of the Bivesiculidae and Hirudinellidae which are reported from deep-sea hosts. These results indicate that only seventeen out of the 150 or so digenean families are reported in the deep sea.
Příspěvek Jana Bati je zprávou o mezinárodní muzikologické konferenci, která se uskutečnila v chorvatském Dubrovníku ve dnech 26. až 28. března 2012., Jan Baťa., Rubrika: Konference, and Cizojazyčné resumé není.
The paper deals with a special way of the construction of the boundary conditions for the compressible gas flow. The solution of the Riemann problem is used at the boundary. It can be shown, that the unknown one-side initial condition for this problem can be partially replaced by the suitable complementary condition. Authors work with such complementary conditions (by the preference of pressure, velocity, total quantities,...) in order to match the physically relevant data. Algorithms were coded and used within the own developed code for the solution of the Euler, NS, and the RANS equations, using the finite volume method. Numerical example shows superior behavior of these boundary conitions in comparison with some other boundary conditions. and Obsahuje seznam literatury
The Treaty on Friendship, Mutual Assistance and Postwar Cooperation between the Czechoslovak Republic and the Union of Soviet Socialist Republics signed on 12 December 1943 in Moscow had a fundamental impact on the orientation of Czechoslovak foreign policy at the end of the war and in the years that followed. At the same time, the lengthy negotiations in 1943, which ultimately resulted in signing the treaty in question, were one of the few moments during the war when Czechoslovakia became the object of an opinion clash between the Great Powers. In this study, which is based primarily on British and US documents (some of which have not been used before), the author analyses in detail the role of the Czechoslovak-Soviet treaty project in the policies of the two Western powers until the signing of the document, before assessing the impact of the treaty in concern on Czechoslovakia’s relations with the United Kingdom and the United States at the end of the war. He points out that neither the British nor the Americans were prepared to conclude a similar treaty with Czechoslovakia since both Western powers wanted the international security system to be based on foundations different from those which had repeatedly failed during the previous three decades. However, the signing of the Czechoslovak-Soviet Treaty dramatically reduced any chance for a federative or confederative arrangement in the region of Central Europe, as well as hopes for a multilateral treaty of alliance ensuring security in this region. For this reason, it was accepted without enthusiasm both in London and in Washington.
C4 photosynthetic pathway and life form were determined for 159 species in 71 genera and 13 families in the grassland of North China. 45 % of the C4 species were found in Graminae, 19 % in each of Cyperaceae and Chenopodiaceae. More than 51 % of these C4 species were in therophyta and 36 % hemicryptophyta, while fewer species were in nanophanerophyta (9 %) or geophyta (5 %). The numbers of C4 species and their life forms were closely related with grassland deterioration and succession in North China. This indicated that the C4 species had greater capacity to tolerate environmental stress (e.g. drought and salinity) caused by animal grazing and cultivation.
When insect herbivores develop over many generations on the same plant species, their descendants may evolve physiological adaptations that enable them to develop more successfully on that plant species than naïve conspecifics. Here, we compared development of wild and lab-reared caterpillars of the cabbage moth, Mamestra brassicae, on a cultivar of cabbage Brassica oleracea (cv. Cyrus) and on a wild plant species, sorrel, Rumex acetosa, on which the wild strain had been collected and reared for two earlier consecutive generations. The lab strain had been reared on the same cabbage cultivar for more than 20 years representing > 200 generations. Survival to adult did not vary with strain or plant species. Both strains, however, developed significantly faster when reared on R. acetosa than B. oleracea. Pupae from the field strain were larger when reared on B. oleracea than on R. acetosa, whereas the identity of the plant species did not matter for the lab strain. Our results show that long-term rearing history on cabbage had little or no effect on M. brassicae performance, suggesting that some generalist herbivores can readily exploit novel plants that may be chemically very different from those on which they have long been intimately associated., Jeffrey A. Harvey, Eke Hengeveld, Miriama Malcicka., and Obsahuje bibliografii