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Start Over Subject Yeast

1. Down-regulation of Model Yeast Proteins by Ubiquitin-dependent Proteolysis

Creator:
Horák, J.
Type:
article, model:article, and TEXT
Subject:
Yeast, Ubiquitin-dependent proteolysis, Vacuole, and Proteasome
Language:
English
Description:
Ubiquitination is a versatile tool used by all eukaryotic organisms for controlling the stability, function, and intracellular localization of a multitude of proteins. I will attempt to bring together our recent data on the down-regulation of twoyeast model proteins, the galactose transporter Gal2 and fructose-1,6-bisphosphatase, by ubiquitin-dependent proteolysis triggered by the additionof easily fermentable carbon sources.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Yeast as a Model Organism to Study Transport and Homeostasis of Alkali Metal Cations

Creator:
Sychrová, H.
Type:
article, model:article, and TEXT
Subject:
Alkali metal cations, Na+/H+ antiporter, Osmotolernce, Plasma membrane, and Yeast
Language:
English
Description:
To maintain an optimum cytoplasmic K+/Na+ ratio, cells employ three distinct strategies: 1) strict discrimination among alkali metal cations at the level of influx, 2) efficient efflux of toxic cations from cells, and 3) selective sequestration ofcations in organelles. Cation efflux and influx are mediated in cells by systems with different substrate specificities and diverse mechanisms, e.g. ATPases, symporters, antiporters, and channels. Simple eukaryotic yeast Saccharomyces cerevisiae cells proved to be an excellent model for studying the transport properties and physiological function of alkali-metal-cation transporters, and the existence of mutant strains lacking their own transport systems provided an efficient tool for a molecular study of alkali-metal-cation tr ansporters from higher eukaryotes upon their expression in yeast cells.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public