Development of gastrointestinal functions

Title:

Development of gastrointestinal functions

Creator:

Koldovský, O., Dobiášová, M., Hahn, P., Kolínská, J., Kraml, J., and Pácha, J.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:baaa6c2a-8b20-47dd-bab6-f031333d1fdc
uuid:baaa6c2a-8b20-47dd-bab6-f031333d1fdc

Subject:

pancreatic amylase, sucrase-isomaltase, maltase-glucoamylase, lactase-phlorizinhydrolase, sialylation of brush border enzymes, glucose transport, pancreatic and small intestinal lipases, esterification capacity, absorption of triglycerides, formation of phospholipids, carnitine absorption, metabolism of the developing small intestine, colonic sodium transport, human fetal studies, adrenal cortex and thyroid gland hormones, "specialization" of intestinal segments, and enterocyte migration

Type:

article, model:article, and TEXT

Description:

Data are summarized about digestion and absorption of carbohydrates, lipids and proteins during mammalian perinatal development including human fetuses. Corresponding with the high fat intake in suckling rats, absorption of triglycerides was found to be approximately 2-3 times higher in suckling than in adult rats. Carnitine contents of the small intestinal mucosa of rats decrease postnatally, reaching adult levels at the time of weaning. Other studies suggested that gluconeogenesis may occur in the small intestine in the neonatal period. The intestinal mucosa of infant rats produces ketones; it was suggested that ketone production is to a large extent due to a breakdown of long-chain fatty acids. Studies dealing with the development of colonic sodium transport in rats are described. Other studies on the developing colon showed that the proximal colon resembles ileum during the early postnatal period. Developmental changes of the "specialization" of intestinal segments are reviewed. In all studies attention is given to the maturative effects of hormones of the adrenal cortex and thyroid gland (88 references).

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1995 Volume:44 | Number:6

Harvested from:

CDK

Metadata only:

false