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572. The effect of wheat allergy on the course of atopic eczema in patients over 14 years of age
- Creator:
- Čelakovská, Jarmila, Ettlerová, Květuše, Ettler, Karel, Vaněčková, Jaroslava, and Bukač, Josef
- Format:
- braille, text, and regular print
- Type:
- model:article, article, Text, and TEXT
- Subject:
- mladiství, dospělí, atopická dermatitida--etiologie--patologie, ženské pohlaví, lidé, imunoglobulin E--krev, mužské pohlaví, Patch Tests, Skin Tests, Wheat Hypersensitivity--co [Complications], and Wheat Hypersensitivity--di [Diagnosis]
- Language:
- English
- Description:
- Few studies concerning the importance of wheat allergy affecting the course of atopic eczema in adolescents and adult patients exist. Aim: The evaluation if wheat allergy can deteriorate the course of atopic eczema. Follow-up of patients with confirmed food allergy to wheat. Method: Altogether 179 persons suffering from atopic eczema were included in the study: 51 men and 128 women entered the study with an average age of 26.2 (s.d. 9.5 years) Dermatological and allergological examinations were performed, including skin prick tests, atopy patch tests, and specific serum IgE for wheat, open exposure test and double-blind, placebo-controlled food challenge test with wheat flour. Results: Wheat allergy affecting the coures of atopic eczema was confirmed in eight patients (4.5%) out of 179 patients enrolled in this study by double-blind, placebo controlled food challenge test. The course of atopic eczema showed a positive trend in patients with confirmed food allergy at 3, 6, 9, 12 month follow-up (statistical evaluation with paired t-test) after the elimination of wheat flour. Conclusion: Wheat allergy may play an important role in the worsening of atopic eczema (acting as a triggering exacerbating factor) only in a minority of adolescents and adult patients (4.5% in our study). The diagnostic methods (skin prick test, specific IgE, atopy patch test, history) cannot be used as separated tests for the determination of food allergy to wheat in patients with atopic eczema.Open exposure tests and double-blind, placebo-controlled food challenge should be used for the confirmation of wheat allergy affecting the course of atopic eczema., Jarmila Čelakovská, Květuše Ettlerová, Karel Ettler, Jaroslava Vaněčková, Josef Bukač, and Literatura 34
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
573. The main approaches to the development of innovative pharmaceutical industry of the Russian Federation in the context of globalization
- Creator:
- Klunko, Natalia and Marynia, Reta
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- farmaceutický průmysl--ekonomika--statistika a číselné údaje--trendy and lidé
- Language:
- English
- Description:
- Pharmaceutical industry - one of the few areas in which innovations affect all of us, because ultimately have a direct impact on the duration and quality of life for us and our loved ones. In the presence of a strong market and a lack of understanding of the need for innovation is necessary, in our opinion, investing in basic research and facilitate the process of innovation in the pharmaceutical industry by the state and society. For the targeted development of pharmaceutical industry seems appropriate to determine at the state level prospects for the domestic pharmaceutical industry and its role in the international market, and develop a drug "doctrine" of Russia. This paper analyzed the problems of the state associated with the pharmaceutical market in the globalization period. Also investigated the theoretical aspects of the modern study of globalization in the light of the analysis for the global pharmaceutical industry and analyzes the major political and economic factors that have the most significant impact on the production of pharmaceuticals., Natalia Klunko, Reta Marynia, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
574. The role of hydrogen peroxide and other reactive oxygen species in wound healing
- Creator:
- Kanta, Jiří
- Format:
- braille, text, and regular print
- Type:
- model:article, article, Text, přehledy, and TEXT
- Subject:
- hojení ran--fyziologie, granulační tkáň--cytologie--chemie, reaktivní formy kyslíku--farmakologie--metabolismus, hyperbarická oxygenace--využití, hypoxie--patofyziologie, peroxidy--farmakologie--terapeutické užití, lidé, and financování organizované
- Language:
- English
- Description:
- Wound healing is a complex physiological process important for tissue homeostasis. An acute injury initiates massive cell migration, proliferation and differentiation, synthesis of extracellular matrix components, scar formation and remodelling. Blood flow and tissue oxygenation are parts of the complex regulation of healing. Higher organisms utilize molecular oxygen as a terminal oxidant. This way of gaining energy for vital processes such as healing leads to the production of a number of oxygen compounds that may have a defensive or informatory role. They may be harmful when present in high concentrations. Both the lack and the excess of reactive oxygen species may influence healing negatively., Jiří Kanta, and Literatura 6
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
575. The use of rubber dam among Czech dental practitioners
- Creator:
- Kapitán, Martin and Šustová, Zdeňka
- Format:
- braille, text, and regular print
- Type:
- model:article, article, Text, and TEXT
- Subject:
- sběr dat, vzorové postupy ve stomatologii--statistika a číselné údaje, ženské pohlaví, lidé, mužské pohlaví, and gumové blány--využití
- Language:
- English
- Description:
- Rubber dam is considered an ideal device for tooth isolation. Nevertheless, its usage is quite rare in the Czech Republic. The aim of this study was: firstly, to gather and evaluate information regarding the use of rubber dam by dentists in the Czech Republic and to compare it with other countries; secondly to find out whether there are any influencing factors as to rubber dam usage; and finally to find out frequency of rubber dam use separately in endodontic treatment and in placing fillings of different materials. A questionnaire-based survey was conducted. Dentists filled in the questionnaires during dental conventions, educational events, conferences and congresses. Rubber dam was routinely used by less than eight per cent of the respondents (n = 35); less than twenty-two per cent of the respondents (n = 97) used rubber dam occasionally, and more than seventy per cent of the respondents (n = 317) has never use it. The results showed that rubber dam is not used frequently in the Czech Republic. If rubber dam is used, then it is typically for endodontic treatment or composite fillings. There were several factors with a statistically significant influence on the usage of rubber dam, such as gender, length of professional career, percentage of direct payments, previous experience in using rubber dam, and undergraduate training in rubber dam use., Martin Kapitán, Zdeňka Šustová, and Literatura 22
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
576. Titul Knihovnice/Knihovník roku Královéhradeckého kraje 2011
- Type:
- model:article, article, and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
577. Tlymphocytes (CD3+HLA-DR+) in patients over 60 with mediterranean spotted fever
- Creator:
- Gospodinova, Margarita
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- marseillská horečka--metabolismus--patofyziologie, imunitní systém--fyziologie, antigeny CD3--fyziologie, imunita buněčná, antigeny CD--fyziologie--metabolismus, T-lymfocyty--fyziologie--metabolismus, HLA-DR antigeny, rickettsiové infekce--diagnóza, statistika jako téma, dospělí, lidé, lidé středního věku, and mladý dospělý
- Language:
- English
- Description:
- Mediterranean spotted fever (MSF) in Bulgaria shows increasing severity, especially in patients over sixty years. As T lymphocytes are the primary effector cells in MSF and are altered by the ageing process we aimed to specify the changes in their numbers in elderly patients. We performed a clinicoepidemiological study, haematological and biochemical analysis of 132 patients of 60+ and 30 patients between 19 and 57 years with MSF. We investigated the cell immunity of 20 patients of 60+ using immunofluocytometry. The control group consisted of 10 younger patients and 10 healthy individuals of 60+. MSF showed more unfavourable course in the elderly.We found T-lymphocytes depletion in all patients with MSF. Activated T lymphocytes were increased in elderly patients with MSF. We found significant differences between the number of activated T lymphocytes in elderly patients and healthy elderly persons. The observed T-lymphocytes depletion in MSF corresponded to the disease severity. The increase in the activated T lymphocytes in patients over 60 years contributes to an adequate immune response., Margarita Gospodinova, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
578. Toxicita léčby, její predikce a kvalita života pacienta
- Creator:
- Mortensen, Hanna R., Lovasová, Zuzana, and Mechl, Zdeněk
- Type:
- model:article, article, Text, abstrakta, and TEXT
- Language:
- Czech
- Description:
- Hanna R. Mortensen, Zuzana Lovasová, Zdeněk Mechl
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
579. Trendy vo výchove gynekologických operatérov
- Creator:
- Mlynček, Miloš
- Type:
- model:article, article, Text, přehledy, and TEXT
- Subject:
- lidé, gynekologické chirurgické výkony--výchova, kontinuální vzdělávání lékařů--normy--organizace a řízení--trendy, odborná praxe--normy--organizace a řízení, odborná způsobilost--normy, pracovní zátěž, oprávnění k praxi--normy--organizace a řízení, výuka - hodnocení--normy, komunikace, kurzy a stáže v nemocnici--organizace a řízení, chybná zdravotní péče--prevence a kontrola, zajištění kvality zdravotní péče, and počítačová simulace
- Language:
- Czech, Slovak, and English
- Description:
- Cieľom prehľadového článku je zdôrazniť najnovšie trendy v chirurgickom tréningu nielen v odbore gynekológia a pôrodníctvo, ale vo všetkých operačných špecializáciách. Bezpečnosť pacientov musí byť najvyššia priorita. V súčasnosti sa kladie veľký dôraz na využívanie simulátorov a na mentálny tréning. Gynekologickí operatéri v 21. storočí by mali ovládať klasickú, vaginálnu, laparoskopickú a robotickú operatívu. Vypracovaný systém vzdelávania v centrách s veľkým počtom operácií a pozitívna pracovná atmosféra sú zásadné faktory v priebehu tréningu., The aim of the review article is to point out the latest trends in the surgical training not only in gynecology and obstetrics but also in all surgical specialties. The safety of the patients must be the highest priority. One of the important areas is the utilization of simulation and mental training in the surgical education. The gynecologic surgeons in the 21st century should be able to perform open, vaginal, laparoscopic and robotic surgical procedures. The established system of education in the high volume centres and positive working climate are crucial factors during surgical training., Miloš Mlynček, and Lit.: 38
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
580. Účinky dioxínov na ľudský organizmus
- Creator:
- Kováč, Ján and Kováč, Daniel
- Format:
- braille, text, and regular print
- Type:
- model:article, article, Text, přehledy, and TEXT
- Subject:
- životní prostředí - znečištění--škodlivé účinky, polychlorované bifenyly--klasifikace--škodlivé účinky--toxicita, dioxiny--škodlivé účinky--toxicita, toxické účinky--metabolismus, biologické markery--analýza, receptory aromatických uhlovodíků - jaderný translokátor, kontaminace potravin--prevence a kontrola, kojení--škodlivé účinky, mateřské mléko--chemie, abnormality zubů--chemicky indukované, novorozenec, kojenec, lidé, krysy, and zvířata
- Language:
- Czech, Slovak, and English
- Description:
- Ján Kováč, Daniel Kováč and Literatura 58
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public