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Start Over Date 2012 Harvested from CDK

352. Fyzioterapie formou hry u pacientů po iktu

Creator:
Kolářová, Barbora, Eliáš, Radek, and Bastlová, Petra
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, práce podpořená grantem, and TEXT
Subject:
lidé, terapie hrou, cévní mozková příhoda--rehabilitace, motorické dovednosti, mužské pohlaví, ženské pohlaví, dospělí, lidé středního věku, hra a hračky, vizuální feedback, and videohra
Language:
Czech and English
Description:
Předmětem této pilotní studie je verifi kace vlivu pozitivních emocí na motorické učení prostřednictvím vizuálního feedbacku formou hry ve virtuálním prostředí u pacientů po iktu. Pilotního měření se zúčastnili 3 pacienti po cévní mozkové příhodě, kteří absolvovali dvoutýdenní terapii formou hry ve virtuálním prostředí. U každého pacienta byla hodnocena před a po terapii posturální stabilita a hrubá motorika paretické horní končetiny pomocí standardizovaného klinického testování (Berg Balance Scale, Action Research Arm Test) i přístrojového vyšetření (dynamická počítačová posturografi e). Z výsledků hodnocení pacientů je zřejmý pozitivní efekt terapie na posturální stabilitu a koordinaci. Hru ve virtuálním prostředí považujeme za vhodný doplněk komplexního fyzioterapeutického přístupu u vybraných pacientů po cévní mozkové příhodě. Vzhledem k výsledkům naší pilotní studie jsou žádoucí další měření zabývající se touto problematikou., This pilot study aims to objectively verify the infl uence of positive emotions on motor learning through visual feedback in the form of games in a virtual environment in individuals aft er a stroke. In this pilot study, we evaluated three stroke patients. They completed a two-week intensive therapy by means of playing virtual games. Postural stability was assessed in every patient before and aft er the therapy, as well as gross motor skills of paretic upper limb by both clinical (Berg Balance Scale, Action Research Arm Test) and instrumental (Dynamic Computed Posturography) testing. The evaluation of patients showed signifi cant positive eff ect of game based therapy on postural stability and coordination. Therefore, playing games in a virtual environment might be considered a suitable addition to the complex of physiotherapeutic approach in patients aft er stroke. In accordance with our pilot measurements, further extension of this study might be useful., Barbora Kolářová, Radek Eliáš, Petra Bastlová, and Literatura 20
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

353. Ganglioneuroblastoma of the thoracic spinal cord: a very rare case report

Creator:
Akgun, Bekir, Ates, Deniz, and Kaplan, Metin
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, kazuistiky, and TEXT
Subject:
ganglioneuroblastom--diagnóza--chirurgie, lidé, kojenec, magnetická rezonanční tomografie, mužské pohlaví, nádory míchy--diagnóza--chirurgie, and hrudní obratle
Language:
English
Description:
An eight-month-old male child was admitted with weakness and swelling in the feet. Paraparesis and bilateral lower extremity edema were present in the neurological examination. Thoracic MRI showed an intradural intramedullary mass 61 × 11 mm in size in the T5–T10 levels. Laminotomy between the T5–T10 vertebrae was performed. A mass with smooth borders was separated from most of the neural tissue. In the postoperative MRI, we observed a contrast enhancing area, considered a residual fragment, only 5 × 4 mm in size. Histopathological properties were compatible with the intermixed subtype of ganglioneuroblastoma. Only a limited number of thoracic cord Ganglioneuroblastoma reports have been previously published. Although very rare in children and young adults, ganglioneuroblastoma should be included in the differential diagnosis of thoracic cord tumors. It is difficult to obtain a preoperative diagnosis with clinical features and radiological investigations. Diagnosis depends on histopathological examinations. Curative treatment should be in the form of a complete resection of the tumor. In partially resected cases, adjuvant radiotherapy may become necessary, along with close follow-up., Bekir Akgun, Deniz Ates, Metin Kaplan, and Literatura 5
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

354. Gender unemployment gaps in the EU: blame the family

Creator:
Bičáková, Alena
Publisher:
CERGE-EI
Format:
electronic and 47 s. : il.
Type:
model:monograph and TEXT
Subject:
Práce, nezaměstnanost, muži a ženy, gender, unemployment, men and women, země Evropské unie, European Union countries, 331.56, 316.346.2, 316.66-055.1/.3, (4), (048.8), 4, and 331
Language:
English and Czech
Description:
Alena Bičáková., Obsahuje bibliografii a bibliografické odkazy, České resumé, and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

358. Genetic variants that participate in oxidation processes and/or oxidative stress and are associated with atherosclerosis

Creator:
Pepalyte, Ingrida, Kučinskiene, Zita Aušrele, Grigalioniene, Kristina, Petrulioniene, Žaneta, Dženkevičiute, Vilma, Bagdonaite, Loreta, and Kučinskas, Vaidutis
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, práce podpořená grantem, and TEXT
Subject:
ateroskleróza--genetika, oxidační stres--genetika, genetické testování, genotyp, fenotyp, biochemická analýza krve, tělesné váhy a míry, počítačová biologie, statistika jako téma, klinické laboratorní techniky, and lidé
Language:
English
Description:
Motivation. Our previous study showed differences in the atherosclerosis phenotype between Lithuanian and Swedish men that could be influenced by complementary factors, namely oxidation processes and/or oxidative stress. The goal of this study was to evaluate the mainstream biological pathways inducing and maintaining the atherosclerotic process by analyzing genetic biomarkers particularly in inflammatory and metabolic pathways where the main focus is laid on the oxidation process. Methods. There were 32 families recruited for the study and clinical as well as biochemical analyses were performed. For genetic analysis 150 SNPs in 89 genes were selected in order to construct a microarray based on Arrayed Primer Extension (APEX) genotyping technology. Genotyping was carried out in 28 families and transmission disequilibrium test (TDT), siblingTDT (STDT), and combined analysis were performed. Results. Clinical and biochemical analysis revealed that probands with premature CAD were more likely to have diabetes mellitus, arterial hypertension, dyslipidemia and were male with high body mass index. Genetic analysis showed six SNPs statistically significantly associated with the atherosclerosis phenotype in the candidate genes ITGA2, IL1B, ALOX5A, OR13G1, MMP9 and NFKB1. These genes belong to different biological pathways: trombocyte adhesion and vessel damage, inflammation response, cholesterol and lypoxygenase metabolic pathway and nutrition. Conclusions. Generalized clinical, biochemical, bioinformatical and candidate genes’ association results support our hypothesis and indicate that the oxidation process may be of key importance in the formation of atherosclerosis., Ingrida Pepalyte, Zita Aušrele Kučinskiene, Kristina Grigalioniene, Žaneta Petrulioniene, Vilma Dženkevičiute, Loreta Bagdonaite, Vaidutis Kučinskas, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

359. Genome-wide association studies in schizophrenia, and potential etiological and functional implications of their results

Creator:
Hosák, Ladislav, Šilhan, Petr, and Hosáková, Jiřina
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, tabulky, přehledy, and TEXT
Subject:
srovnávací asociační studie genomů, lidé, and schizofrenie--genetika
Language:
English
Description:
Background: Despite the fact that the genetic basis of schizophrenia has been intensively studied for more than two decades, our contemporary knowledge in this field is rather fractional, and a substantial part of it is still missing. The aim of this review article is to sum up the data coming from genome‑wide association genetic studies in schizophrenia, and indicate prospective directions of further scientific endeavour. Methods: We searched the National Human Genome Research Institute’s Catalog of genome‑wide association studies for schizophrenia to identify all papers related to this topic. In consequence, we looked up the possible relevancy of these findings for etiology and pathogenesis of schizophrenia using the computer gene and PubMed databases. Results: Eighteen genome‑wide association studies in schizophrenia have been published till now, referring to fifty‑seven genes supposedly involved into schizophrenia’s etiopathogenesis. Most of these genes are related to neurodevelopment, neuroendocrinology, and immunology. Conclusions: It is reasonable to predict that complex studies of sufficiently large samples, involving detection of copy number variants and assessment of endophenotypes, will produce definitive discoveries of genetic risk factors for schizophrenia in the future., Ladislav Hosák, Petr Šilhan, Jiřina Hosáková, and Literatura 48
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

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