Linear relations, containing measurement errors in input and output data, are taken into account in this paper. Parameters of these so-called \emph{errors-in-variables} (EIV) models can be estimated by minimizing the \emph{total least squares} (TLS) of the input-output disturbances. Such an estimate is highly non-linear. Moreover in some realistic situations, the errors cannot be considered as independent by nature. \emph{Weakly dependent} (α- and φ-mixing) disturbances, which are not necessarily stationary nor identically distributed, are considered in the EIV model. Asymptotic normality of the TLS estimate is proved under some reasonable stochastic assumptions on the errors. Derived asymptotic properties provide necessary basis for the validity of block-bootstrap procedures.
The variance of the number of lattice points inside the dilated bounded set $rD$ with random position in $\Bbb R^d$ has asymptotics $\sim r^{d-1}$ if the rotational average of the squared modulus of the Fourier transform of the set is $O(\rho ^{-d-1})$. The asymptotics follow from Wiener's Tauberian theorem.
Cíl práce: Prezentujeme kazuistiku pacienta, u kterého došlo k rozvoji oboustranného seminomu na podkladě intratubulární germinální neoplazie – neklasifikovatelný typ (IGCNU – intratubular germ cell neoplasia unclassified type). Kazuistika: Pacient s anamnézou seminomu levého varlete klinického stadia I a IGCNU po radikální orchiektomii a adjuvantní radioterapii byl odeslán k urologickému vyšetření pro suspektní tumor solitárního pravého varlete dle sonografického vyšetření. Indikovali jsme 3biopsii varlete, která prokázala přítomnost IGCNU. Následovala radikální orchiektomie, kde byl histologicky verifikován klasický seminom. Závěr: Intratubulární germinální neoplazie představuje vysoké riziko rozvoje invazivního germinálního tumoru varlete. Léčba zahrnuje radioterapii či chemoterapii cisplatinou. Alternativou je pečlivá dispenzarizace a pravidelné sonografické kontroly, zejména u pacientů se solitárním varletem, kteří chtějí zachovat fertilitu a endokrinní funkci. Biopsie kontralaterálního varlete u pacientů s germinálním tumorem k vyloučení IGCNU by měla být provedena v případě kryptorchizmu, poruchy spermiogeneze a atrofií varlete s objemem pod 12 ml, vhodná je rovněž u pacientů s mikrolitiázou varlete a předchozím výskytem IGCNU., Objective: We are presenting a case report of young man who developed an asynchronous bilateral seminoma based on an intratubular germ cell neoplasia of unclassified type (IGCNU). Case report: A patient, with history of a stage I seminoma of the left testis, based on an IGCNU of the left testis, after a radical orchidectomy and adjuvant radiotherapy, was referred to the urology clinic with a suspected tumor of the right testis. A testicular biopsy was made and the histological examination showed an IGCNU. A radical orchidectomy was performed and a seminoma was found. Conclusion: IGCNU is a precursor lesion of germ cell testicular tumors. Treatment of the IGCNU includes radiotherapy or chemotherapy with cisplatin. Surveillance remains an option for those with a solitary testicle who wish to preserve fertility and endocrine function. A contralateral testicular biopsy, in patients with a history of germ cell tumors, should be made in cases of cryptorchidism, poor spermatogenesis, and testicular atrophy with a testicular volume of less than 12 ml. Biopsy is also recommended in patients with testicular microlithiasis and history of ITGCNU., Jakub Musil, Daniel Bulíř, Jan Jandejsek, and Literatura
V našem článku prezentujeme případ 72letého pacienta s asynchronní nádorovou kvadruplicitou, z toho synchronní duplicitou urologických malignit. U tohoto pacienta byly postupně diagnostikovány a léčeny následující zhoubné nádory: seminom pravého varlete, kolorektální karcinom, seminom levého varlete a adenokarcinom prostaty., We present a case report of 72-year-old male with asynchronous cancer quadruplicity including synchronous duplicity of urological malignanties. He has been diagnosed and treated for seminoma of the right testis, colorectal carcinoma, seminoma of the left testis and adenocarcinoma of the prostate., Martin Klíma, Jan Schraml, Marek Broul, Martin Hlavička, Petr Skála, Martin Čegan, Martina Chodacká, and Literatura
This paper studies the leader-following consensus problem of second-order multi-agent systems with directed topologies. By employing the asynchronous sampled-data protocols, sufficient conditions for leader-following consensus with both constant velocity leader and variable velocity leader are derived. {Leader-following quasi-consensus can be achieved in multi-agent systems when all the agents sample the information asynchronously.} Numerical simulations are provided to verify the theoretical results.
In the 20th century was the fate of the Assyrian people, the so called „Nestorians”, one of the smallest Christian communities of the Near East, full of oppression, suffering and sorrows. After the general genocide in Ottoman Turkey and Persia during the WWI there was a mass flight to the USA, Europe and Russia. The article describes the Assyrian-Russian relations during the last century and making a large diaspora in Eastern Europe. Special attention is paid to the Assyrians’ contribution to the Russian society and their current social and religious status.