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273562. EAHIL Workshop 2009
- Type:
- model:article, article, and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273563. EAHIL Workshop 2011
- Type:
- model:article, article, and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273564. EAHIL Workshop 2013
- Type:
- model:article, article, and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273565. EAHIL Workshop 2015
- Type:
- model:article, article, and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273566. Earliest pottery in Eurasia continent
- Creator:
- Pavlů, Ivan, Machová, Tereza, and Pchálková, Alžběta
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- Neolithic, Mesoneolithic, Palaeoneolithic, Pleistocene, Holocene, Siberia, Eurasia, neolit, mesoneolit, paleoneolit, pleistocén, holocén, Sibiř, and Eurasie
- Language:
- Czech
- Description:
- This paper presents an overview of the latest information about the beginnings of the technology of pottery making in the area of the forest-steppe belt in Siberia and the Russian part of Eastern Europe all the way to the Ural Mountains. From a continental point of view, a brief spatiotemporal diagram presents a completely different background of the beginnings of pottery in our lands and also in corresponding parts of Southeast Europe, where the origin of pottery has traditionally been linked to the Neolithisation of Europe. The earliest pottery technology in China dates back to 20 000 BP, followed by all the subsequent data from the Far East area to Lake Baikal. The earliest pottery culture, Jomon, which had been developing in Japan for more than ten thousand years, is not included here. In the Russian part of Eastern Europe, pottery technology starts developing only after 8 000 BP. Typologically uniform and mostly unchangeable development of beaker-shaped pottery, mostly with a pointed bottom, is common for both these areas. This development continues in Scandinavia and adjacent areas of the Baltic and in Atlantic Europe. In the central parts of Europe, similar shapes only occur sporadically in the earliest period. However, the earliest Eurasian pottery had influenced the development of later prehistoric periods. Numerous settlement groups on the Eurasian continents were characterised by two traditions that are archaeologically recognisable. In simple terms, one of the traditions was agricultural, the other conservative. and Práce předkládá přehled nejnovějších informací o počátcích technologie výroby keramiky v oblastech lesostepního pásma Sibiře a ruské východní Evropy až k Uralu. Data nejstarší keramické technologie v Číně přesahují číslo 20 tis. BC. Na území ruské východní Evropy začíná vývoj keramické technologie většinou až po roce 8000 BC. Obě oblasti spojuje typologicky jednotný a málo proměnlivý vývoj kotlovitých tvarů převážně se špičatým dnem. Na tento vývoj navazuje srovnatelně kulturní posloupnost ve Skandinávii a v přilehlých oblastech Baltu i Evropského pobřeží Atlantiku. V centrálních oblastech Evropy se podobné tvary vyskytnou v nejstarším období zcela ojediněle. Eurasijská nejstarší keramika však nepochybně ovlivnila vývoj i v pozdějších pravěkých obdobích. Početné skupiny osídlení na evropském i eurasijském kontinentu se vyznačovaly dvojí tradicí hmatatelnou archeologicky nejen v keramice. Zjednodušeně řečeno, jedna byla zemědělská, druhá konzervativní.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273567. Early and late allergic phase related cough response in sensitized guinea pigs with experimental allergic rhinitis
- Creator:
- Brozmanová, M., Čalkovský, V. , Plevková, J. , Bartoš, V. , Plank, L., and Tatár, M.
- Type:
- article, model:article, and TEXT
- Subject:
- Allergic inflammation, Experimental allergic rhinitis, Ovalbumin, Citric acid - induced cough, and Guinea pig
- Language:
- English
- Description:
- Cough is a common and important symptom of asthma and allergic rhinitis. Previous experimental evidence has shown enhanced cough sensitivity during early phase of experimental allergic rhinitis in guinea pigs. We hypothesized that airway inflammation during the late phase response after repeated nasal antigen challenge may affect the afferent sensory nerve endings in the larynx and tracheobronchial tree and may also modulate cough response. In the present study we evaluated the cough sensitivity during a period of early and late allergic response in sensitized guinea pigs after repeated nasal antigen challenges. Forty-five guinea pigs were sensitized with ovalbumin (OVA). Four weeks later 0.015 ml of 0.5 % OVA was intranasally instilled to develop a model of allergic rhinitis that was evaluated from the occurrence of typical clinical symptoms. Animals were repeatedly intranasally challenged either by OVA (experimental group) or by saline (controls) in 7-day intervals for nine weeks. Cough was elicited by inhalation of citric acid aerosols. Cough was evaluated at 1 or 3 h after the 6th nasal challenge and 17 or 24 h after the 9th nasal challenge. The cough reflex was significantly increased at 1 and 3 h after repeated nasal challenge in contrast to cough responses evoked at 17 and 24 h after repeated nasal challenge. In conclusion, enhanced cough sensitivity only corresponds to an early allergic response after repeated nasal challenges.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
273568. Early and late effects of hyperbaric oxygen treatment on oxidative stress parameters in diabetic patients
- Creator:
- Gürdöl, Figen, Cimşit, M., Öner-İyidoğan, Y., Körpinar, Ş., Yalçinkaya, S., and Koçak, H.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Biochemie. Molekulární biologie. Biofyzika, biochemie, hyperbarická oxygenoterapie, diabetická noha, biochemistry, hyperbaric medicine, diabetic foot, isoprostanes, malondialdehyde, advanced oxidation protein products, 2, and 577
- Language:
- English
- Description:
- Exposure to hyperbaric oxygen leads to increased amount of reactive oxygen species (ROS) that are derived from various sources. After the discovery that ROS can function as signaling molecules, the idea of ROS being hazardous to biological tissues has been challenged. The aim of this study was to examine the changes in oxidative stress parameters in diabetics undergoing hyperbaric oxygen therapy (HBOT) due to foot ulcers. Twenty patients, who received HBOT for diabetic foot ulcers, were included in the study. Blood samples were taken before HBOT and 30 min after exit from the chamber, on the day of the first and the 15th HBOT sessions. They were used for the determinations of malondialdehyde (MDA), 8-isoprostane and advanced oxidation protein products (AOPPs). 8-Isoprostane and AOPP levels were not altered significantly after the first HBOT session, while both were increased on the fifteenth day (p<0.05). MDA was significantly increased only after the first HBOT session, and remained unchanged on the fifteenth day (within-day variations). Plasma AOPP levels were lowered significantly after fifteen consecutive HBOT sessions (between-day variations). Decreased AOPP levels suggest that increased oxygenation of tissues due to HBO therapy may activate some endogenous factors that prevent hazardous effects of the disease itself., F. Gürdöl, M. Cimşit, Y. Öner-İyidoğan, Ş. Körpinar, S. Yalçinkaya, H. Koçak., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
273569. Early cardiac injury in acute respiratory distress syndrome: comparison of two experimental models
- Creator:
- Mikolka, Pavol, Kosutova, Petra, Balentova, Sona, Cierny, Daniel, Kopincova, Jana, Kolomaznik, Maros, Adamkov, Marian, Calkovska, Andrea, and Mokra, Daniela
- Format:
- počítač and online zdroj
- Type:
- model:article and TEXT
- Subject:
- acute respiratory distress syndrome, cardiac injury, oxidative stress, inflammation, and apoptosis
- Language:
- English
- Description:
- Acute respiratory distress syndrome (ARDS) is characterized by diffuse lung damage, inflammation, oedema formation, and surfactant dysfunction leading to hypoxemia. Severe ARDS can accelerate the injury of other organs, worsening the patient´s status. There is an evidence that the lung tissue injury affects the right heart function causing cor pulmonale. However, heart tissue changes associated with ARDS are still poorly known. Therefore, this study evaluated oxidative and inflammatory modifications of the heart tissue in two experimental models of ARDS induced in New Zealand rabbits by intratracheal instillation of neonatal meconium (100 mg/kg) or by repetitive lung lavages with saline (30 ml/kg). Since induction of the respiratory insufficiency, all animals were oxygen-ventilated for next 5 h. Total and differential counts of leukocytes were measured in the arterial blood, markers of myocardial injury [(troponin, creatine kinase - myocardial band (CK-MB), lactate dehydrogenase (LD)] in the plasma, and markers of inflammation [tumour necrosis factor (TNF)α, interleukin (IL)-6], cardiovascular risk [galectin-3 (Gal-3)], oxidative changes [thiobarbituric acid reactive substances (TBARS), 3-nitrotyrosine (3NT)], and vascular damage [receptor for advanced glycation end products (RAGE)] in the heart tissue. Apoptosis of heart cells was investigated immunohistochemically. In both ARDS models, counts of total leukocytes and neutrophils in the blood, markers of myocardial injury, inflammation, oxidative and vascular damage in the plasma and heart tissue, and heart cell apoptosis increased compared to controls. This study indicates that changes associated with ARDS may contribute to early heart damage what can potentially deteriorate the cardiac function and contribute to its failure.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
273570. Early changes during skin repair using tissue-engineered dermal template in a full-thickness burn
- Creator:
- Gál, P., Fröhlichová, L., Čoma, M., Pafčuga, I., Šuca, H., Grossová, I., Hríbiková, Z., Sticová, E., and Zajíček, R.
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- wound healing, angiogenesis, artificial skin, tissue engineering, and burn injury
- Language:
- English
- Description:
- Rapid wound closure in extensively burned patients has remained one of the major unresolved issues of medicine. Integra® is the most widely established artificial skin, which is composed of a porous matrix of cross-linked bovine collagen and chondroitin 6-sulphate covered by a semi-permeable silicone layer. We present here a (immuno)histological study of a severely burned patient with a full-thickness burn treated with a tissue-engineered dermal template (Integra®) and split-thickness skin graft-based protocol. Immunohistochemical investigation of the artificial dermis revealed that immune cell infiltration reached its peak on day 10. Tissue immunophenotyping found an increase in CD3+ cells over the course of the study as well as CD4 and CD8 positivity on day 40, indicating remaining T-cell subpopulations. We observed weak/no infiltration of NK cells (CD56+). In conclusion, the use of bi-layer Integra® represents a feasible and safe procedure resulting in formation of non-irritating dermal substitutes.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public