Pod názvem: Canadian Photography Institute of the National Gallery of Canada, Jeu de Paume, "Published in conjunction with the exhibition ... organized by the Canadian Photography Institute of the National Gallery of Canada in collaboration with the Jeu de Paume for the presentation in Paris. Exhibition tour: Jeu de Paume, Paris 7 June - 25 September, 2016, National Gallery of Canada, Ottawa 28 October, 2016 - 19 March, 2017."--Rub titulní stránky, Životopisná data, přehled výstav a zastoupení ve sbírkách, and Chronologický přehled
Large animal models to explore the safety and tolerability of novel therapeutic approaches for Huntington’s disease (HD) are in exploration to achieve higher translational reliability in future studies. Recently, a Libechov minipig has been established as one new transgenic (Tg) large animal model for HD. We here discuss the advantages and limitations in using this model in HD with regards to breeding, housing, handling, and with respect to homology to humans and ethical considerations. A group of TgHD and wild type (WT) female minipigs (n = 36) was used to gain first evidence about abovementioned aspects. It is concluded that Libechov minipigs may fulfill an important role to bridge the gap between rodents and non‑human primates in the translation to humans. and S. Schramke, R. Schubert, F. Frank, M. Wirsig, M. Fels, N. Kemper, V. Schuldenzucker, R. Reilmann