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3382. Periodicity of arrhythmias in healthy elderly men at the moderate altitude
- Creator:
- Štefan Kujaník, Marian Sninčák, Vokáľ, J., Juraj Podracký, and Juraj Kovaľ
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, elektrokardiografie, srdeční arytmie, biorytmy, electrocardiography, cardiac arrhythmia, biological rhythms, holter ECG monitoring, altitude, 14, and 612
- Language:
- English
- Description:
- The 24-hour periodicity of supraventricular (SVPB) and ventricular (VEB) extrasystoles in healthy elderly men (age 49-69 years) was studied at two altitudes during 24 h Holter ECG monitoring. At the low altitude (200 m, n = 26), SVPB were more frequent than VEB. The highest occurrence of SVPB was at 17:00 h, the lowest at 01:00 and 02:00 h (P<0.001). The highest occurrence of VEB was at 09:00 h, the lowest one at 04:00 h (P<0.001). At 1350 m (n=9) the incidence of both SVPB and VEB was approximately twofold higher compared to that at the low altitude (P<0.001). The highest occurrence of SVPB was at 13:00 h, the lowest at 06:00 h (P<0.001). VEB were the most frequent at 10:00 h and 13:00 h, while the lowest frequency was observed at 06:00 h (P<0.001). Our results indicate that the incidence of SVPB and VEB in healthy persons at the moderate altitude is twofold and its periodicity is shifted compared to the low altitude. The cause of increased occurrence of extrasystoles is probably due to β-adrenergic activation of the heart at the higher altitude., Š. Kujaník, M. Sninčák, J.Vokáľ, J. Podracký, J. Koval., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
3383. Periodická řešení Einsteinových rovnic
- Creator:
- Scholtz, Martin
- Format:
- Type:
- model:article and TEXT
- Subject:
- fyzika, physics, 6, and 53
- Language:
- Czech and English
- Description:
- In the Newtonian theory of gravity, exact solutionsof the two-body problem are well known, while in general relativity we expect that periodic solutions cannot describe isolated systems. In the presented paper we give a rigorous proof of the non-existence of asymptotically flat periodic solutions to Einstein's equations. Moreover, we introduce several mathematical methods used in the proof., V newtonovské teorii gravitace jsou dobře známá přesná periodická řešení dvoučásticového systému, zatímco v obecné teorii relativity očekáváme, že periodická řešení Einsteinových rovnic nemohou popisovat izolované systémy. V článku podáváme rigorózní důkaz neexistence asymptoticky plochých periodických řešení Einsteinovych rovnic a vysvětlujeme matematické metody v důkazu použité., Martin Scholtz., and Obsahuje seznam literatury
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
3384. Periods of dormancy and cohort-splitting in the millipede Polydesmus angustus (Diplopoda: Polydesmidae)
- Creator:
- David, Jean-François, Celerier, Marie-Louise, and Geoffroy, Jean-Jacques
- Format:
- print, text, and regular print
- Type:
- article, bibliography, conference publication, model:article, and TEXT
- Subject:
- Third European Workshop of Invertebrate Ecophysiology (1998 : Birmingham, Česko), zoologie, fyziologie živočichů, ekofyziologie, hmyz, Diplopoda, Polydesmus angustus, životní cyklus, reprodukční dormance, diapauza, sezónní vlivy, 591.5, 061.3, and 595.2/.7
- Language:
- English
- Description:
- First stadium juveniles of P. angustus were reared under controlled seasonal conditions to maturity, reproduction and death. Individuals born in any one breeding season either had a 1-year or a 2-year life cycle (cohort-splitting). The life cycle was annual for individuals born in the first part of the breeding season (May-August), but became biennial for those born later (August-October). Two phenomena were involved: (1) Only individuals reaching the penultimate stadium (stadium VII) before a critical period at the end of spring could become adult in the breeding season following that of their birth. After this time, stadium VII individuals entered into aestivation and only became adult in the second autumn after their birth. (2) Females becoming adult in autumn entered reproductive dormancy and only laid eggs in the following spring. Overall, individuals born at the start of the breeding season easily reached stadium VII before the critical period and were able to breed at I year, whereas individuals born at the end of the breeding season reached stadium VII after the critical period, then had two consecutive periods of dormancy and only bred at 2 years age. Individuals from the same nest born in the middle of the breeding season (August) could have either annual or biennial life cycles, depending on whether they reached stadium VII before or during aestivation. The environmental factors capable of triggering aestivation in subadults and reproductive dormancy in autumn-maturing females are discussed., Jean-Francois David, Marie-Louise Celerier, Jean-Jacques Geoffroy, and Lit
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
3385. Perioperační péče a diabetes
- Creator:
- Šmahelová, Alena
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, přehledy, and TEXT
- Subject:
- lidé, diabetes mellitus--farmakoterapie, komplikace diabetu, perioperační období, perioperační péče--metody, pooperační komplikace--prevence a kontrola, krevní glukosa--metabolismus, inzulin--aplikace a dávkování, časové faktory, hypoglykemika--aplikace a dávkování, and antidiabetická léčba
- Language:
- Czech and English
- Description:
- Perioperační péče o diabetika je specifická nejen nezbytností adekvátní korekce glykemie, ale také výskytem komplikací, které se u nediabetiků nevyskytují. Dosavadní antidiabetickou léčbu je proto většinou nutno přizpůsobit perioperačnímu období, u malých a krátkých chirurgických výkonů to však není většinou nutné. Perioperační péči je nezbytné u diabetiků pečlivě zorganizovat a naplánovat. K hlavním zásadám patří adekvátní monitoring glykemií a inzulinové terapie, zajištění nutrice a provedení výkonu ráno., The perioperative care of diabetic patients is specific due to the necessity of adequate glycaemic correction, as well as owing to the occurrence of complications not taking place in nondiabetic patients. The present antidiabetic treatment therefore mostly needs to be adjusted to the perioperative period, but this is largely not necessary in the case of small and short surgeries. The perioperative care of diabetic patients must be carefully organized and scheduled. The main rules include adequate monitoring of blood glucose and insulin therapy, provision of nutrition and surgery performance in the morning., and Alena Šmahelová
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
3386. Perioperační péče na gynekologickém oddělení
- Creator:
- Wolfová, Petra, Filausová, Drahomíra, and Belešová, Romana
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, and TEXT
- Subject:
- perioperační péče--metody--psychologie, gynekologicko-porodnické oddělení nemocnice, gynekologické chirurgické výkony, spokojenost pacientů, šíření informací, péče o pacienta--metody--psychologie, sběr dat, porodní asistentky, dospělí, staří, ženské pohlaví, lidé, and lidé středního věku
- Language:
- Czech and English
- Description:
- Článek informuje o výzkumném šetření, které proběhlo v roce 2014 na gynekologickém oddělení. Kromě výsledků výzkumného šetření jsou zde stručně popsány i operační přístupy využívané v gynekologii, perioperační péče u klientek poskytovaná porodními asistentkami a také potřeby žen v tomto období., The article informs about the research which was carried out at gynaecology department in 2014. Except the results of research there are briefly described surgical approaches used in gynaecology, perioperative care of clients provided by midwives and the needs of women in this period., and Petra Wolfová, Drahomíra Filausová, Romana Belešová
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
3387. Peripheral sensitivity to steroids revisited
- Creator:
- Richard Hampl and Karel Vondra
- Format:
- print, bez média, and svazek
- Type:
- article, články, journal articles, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, steroidní hormony, glukokortikoidy, estrogeny, steroid hormons, glucocorticoids, estrogens, androgen, receptor, resistance, 14, and 612
- Language:
- English
- Description:
- Resistance to steroid hormones presents a serious problem with respect to their mass use in therapy. It may be caused genetically by mutation of genes involved in hormonal signaling, not only steroid receptors, but also other players in the signaling cascade as co-regulators and other nuclear factors, mediating the hormone-born signal. Another possibility is acquired resistance which may develop under long-term steroid treatment, of which a particular case is down regulation of the receptors. In the review recent knowledge is summarized on the mechanism of main steroid hormone action, pointing to already proven or potential sites causing steroid resistance. We have attempted to address following questions: 1) What does stay behind differences among patients as to their response to the (anti)steroid treatment? 2) Why do various tissues/cells respond differently to the same steroid hormone though they contain the same receptors? 3) Are such differences genetically dependent? The main attention was devoted to glucocorticoids as the most frequently used steroid therapeutics. Further, androgen insensitivity is discussed with a particular attention to acquired resistance to androgen deprivation therapy of prostate cancer. Finally the potential causes are outlined of breast and related cancer(s) resistance to antiestrogen therapy., R. Hampl, K. Vondra., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
3388. Periprosthetic osteolysis and its association with RANKL expression
- Creator:
- David Veigl, Jaroslava Niederlová, and Olga Kryštůfková
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, ortopedie, leptin, human physiology, orthopedics, RANK, RANKL, periprostetická osteolýza, RANKL (receptor activator of nuclear factor kappa B ligand), periprosthetic osteolysis, 14, and 612
- Language:
- English
- Description:
- Extensive osteolysis adjacent to orthopedic implants is often associated with wear particles of prosthetic material. The activation of the RANKL/RANK/OPG system is considered to be a likely cause of periprosthetic osteolysis leading to implant failure. The aim of this study was to examine the possible correlation between the clinical extent of osteolysis, the number of wear particles and expression of the osteoclastic mediator RANKL (receptor activator of nuclear factor kappa B ligand) in the tissues aro und aseptically loosened cemented and non-cemented total hip replacements. Periprosthetic tissues were harvested from 59 patients undergoing revision of hip replacement for aseptic loosening. We observed RANKL-positive cells in 23 of our 59 patients, their presence was noted predominantly in tissues with a loosened cemented endoprosthesis. We have found that RANKL is present only in tissues with a large amount of wear debris and predominantly in cases involving loosened cemented implants., D. Veigl, J. Niederlová, O. Kryštůfková., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
3389. Permakultura Integra aneb Martin Luther a GM plodiny
- Creator:
- Opatrný, Zdeněk
- Format:
- 118-125, print, text, and regular print
- Type:
- model:article, article, Text, biography, historické články, and TEXT
- Subject:
- rostliny geneticky modifikované--fyziologie--genetika, ekologie, and zemědělství--metody--trendy
- Language:
- Czech and English
- Description:
- Článek Permakultura? Mojmíra Vlašína z p rvního čísla časopisu Anthropologia integra nabízí čtenářům lákavou představu eko- logicky šetrné technologie pěstování kulturních plodin, nevyžadující aplikace pesticidů či minerálních hnojiv, energeticky minimálně náročné a p řitom poskytující více potravin než třeba obilné pole. Z p ohledu současné vědy o r ostlinách je ovšem možnost realizace takto efektivních permakultur pro dostatečnou výživu rostoucí lidské populace čirou mystifikací. Text polemiky nejen dokládá nereálnost tvrzení zmíněného článku, ale také nabízí jinou, vědecky podloženou alternativu moderního, vysoce produktivního a p řitom ekologicky šetrného zemědělství, vy- cházejícího z v yužití nejrůznějších typů geneticky modifikovaných (GM) plodin. Její přínos a d e facto budoucí nezbytnost pro světový boj proti hladu a c hudobě ilustruje s p omocí „ammanovských tezí“, shrnujících závěry nedávných jednání jednak vatikánské Pontifikální Akademie, jednak předních německých vědeckých společností., The contribution of Mojmír Vlašín entitled Permaculture? and published in the first issue of Anthropologia Integra offered to its readers attractive view on the ecologically friendly technology of the crop production, supposed to supply growing human population with the sufficient food amount. As postulated, in permaculture praxis no mineral fertilization, no pesticide application would be necessary to produce more edible biomass then conventional cereal field is able to provide. Unfortunately, from the point of view of recent plant biology the realization of similar world permaculture appears to be pure mystification. The only modern alternative to make existing conventional agrotechnologies both more effective and also ecologically friendly represents the application of various GM crops. The “Amman’s Thesis” based on the conclusions and recommendations of some recent European high reputation meetings (Pontifical Academy of Sciences, Leopol- dina, German Academy of Sciences) illustrates unique asset of the GM technologies in solution of the world hunger, malnutrition and human poverty problems., Zdeněk Opatrný, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
3390. Permanent depression of plasma cGMP during long-term space flight
- Creator:
- Rössler, A., Noskov, V., László, Z., Polyakow, V. V., and Helmut Hinghofer-Szalkay
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, Long-duration space flight, head-down tilt, cyclic guanosine monophosphate, atrial natriuretic peptide, bed rest, 14, and 612
- Language:
- English
- Description:
- The purpose of this study was to investigate plasma concentrations of cyclic guanosine monophosphate (cGMP) and atrial natriuretic peptide (ANP) during and after real and simulated space flight. Venous blood was obtained 3 min after the beginning and 2 min after the lower body negative pressure maneuver in two cosmonauts preflight (supine), inflight, and postflight (supine) and in five other subjects before, at the end, and 4 days after a 5-day head-down tilt (-6°) bed rest. In cosmonaut 1 (10 days in space), plasma cGMP fell from preflight 4.3 to 1.4 nM on flight day 6, and was 3.0 nM on the fourth day after landing. In cosmonaut 2 (438 days in space), it fell from preflight 4.9 to 0.5 nM on on flight day 3, and stayed <0.1 nM with 5, 9, and 14 months in space, as well as on the fourth day after landing. Three months after the flight his plasma cGMP was back to normal (6.3 nM). Cosmonaut 2 also displayed relatively low inflight ANP values but returned to preflight level immediately after landing. In a ground-based simulation on five other persons, supine plasma cGMP was reduced by an average of 30 % within 5 days of 6° head-down tilt bed rest. The data consistently demonstrate lowered plasma cGMP with real and simulated weightlessness, and a complete disappearance of cGMP from plasma during, and shortly after long-duration space flight., A. Rössler, V. Noskov, Z. László, V.V. Polyakow, H. G. Hinghofer-Szalkay., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public